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Changelog: https://cryptography.io/en/latest/changelog/#v2-4-2 Important changes: - BACKWARDS INCOMPATIBLE: Dropped support for LibreSSL 2.4.x. - Deprecated OpenSSL 1.0.1 support. OpenSSL 1.0.1 is no longer supported by the OpenSSL project. At this time there is no time table for dropping support, however we strongly encourage all users to upgrade or install cryptography from a wheel.