This allows one to add rules which change a packet's routing table:
iptables -t raw -I PREROUTING 1 -m set --match-set myset src -j MARK --set-mark 2
ip rule add fwmark 2 table 1 priority 1000
ip route add default dev wg0 table 1
to the beginning of raw table PREROUTING chain, and still have rpfilter.