diff --git a/pkgs/applications/graphics/djview/default.nix b/pkgs/applications/graphics/djview/default.nix
index 85c0f58174a..2b0dde210c5 100644
--- a/pkgs/applications/graphics/djview/default.nix
+++ b/pkgs/applications/graphics/djview/default.nix
@@ -1,5 +1,6 @@
 { stdenv, fetchurl, pkgconfig
-, djvulibre, qt4, xorg, libtiff }:
+, djvulibre, qt4, xorg, libtiff
+, darwin }:
 
 stdenv.mkDerivation rec {
   name = "djview-${version}";
@@ -12,7 +13,8 @@ stdenv.mkDerivation rec {
 
   nativeBuildInputs = [ pkgconfig ];
 
-  buildInputs = [ djvulibre qt4 xorg.libXt libtiff ];
+  buildInputs = [ djvulibre qt4 xorg.libXt libtiff ]
+  ++ stdenv.lib.optionals stdenv.isDarwin [ darwin.apple_sdk.frameworks.AGL ];
 
   passthru = {
     mozillaPlugin = "/lib/netscape/plugins";
diff --git a/pkgs/development/libraries/botan/generic.nix b/pkgs/development/libraries/botan/generic.nix
index 4a4ec5d9fe9..b37fd6079b9 100644
--- a/pkgs/development/libraries/botan/generic.nix
+++ b/pkgs/development/libraries/botan/generic.nix
@@ -3,6 +3,7 @@
 , baseVersion, revision, sha256
 , extraConfigureFlags ? ""
 , postPatch ? null
+, darwin
 , ...
 }:
 
@@ -20,7 +21,8 @@ stdenv.mkDerivation rec {
   };
   inherit postPatch;
 
-  buildInputs = [ python bzip2 zlib gmp openssl boost ];
+  buildInputs = [ python bzip2 zlib gmp openssl boost ]
+             ++ stdenv.lib.optional stdenv.isDarwin darwin.apple_sdk.frameworks.Security;
 
   configurePhase = ''
     python configure.py --prefix=$out --with-bzip2 --with-zlib ${if openssl != null then "--with-openssl" else ""} ${extraConfigureFlags}${if stdenv.cc.isClang then " --cc=clang" else "" }
diff --git a/pkgs/development/libraries/liblastfm/default.nix b/pkgs/development/libraries/liblastfm/default.nix
index 0beb689090a..aa76505c3a0 100644
--- a/pkgs/development/libraries/liblastfm/default.nix
+++ b/pkgs/development/libraries/liblastfm/default.nix
@@ -1,4 +1,5 @@
-{ stdenv, fetchurl, qt4, pkgconfig, libsamplerate, fftwSinglePrec, which, cmake }:
+{ stdenv, fetchurl, qt4, pkgconfig, libsamplerate, fftwSinglePrec, which, cmake
+, darwin }:
 
 let version = "1.0.9"; in
 
@@ -15,6 +16,7 @@ stdenv.mkDerivation rec {
   prefixKey = "--prefix ";
   propagatedBuildInputs = [ qt4 libsamplerate fftwSinglePrec ];
   nativeBuildInputs = [ pkgconfig which cmake ];
+  buildInputs = stdenv.lib.optional stdenv.isDarwin darwin.apple_sdk.frameworks.SystemConfiguration;
 
   meta = {
     homepage = http://github.com/lastfm/liblastfm;
diff --git a/pkgs/development/libraries/wxsqlite3/default.nix b/pkgs/development/libraries/wxsqlite3/default.nix
index 88cf92b34ef..a0600399784 100644
--- a/pkgs/development/libraries/wxsqlite3/default.nix
+++ b/pkgs/development/libraries/wxsqlite3/default.nix
@@ -1,4 +1,5 @@
-{ stdenv, fetchFromGitHub, wxGTK, sqlite }:
+{ stdenv, fetchFromGitHub, wxGTK, sqlite
+, darwin }:
 
 stdenv.mkDerivation rec {
   name = "wxsqlite3-${version}";
@@ -11,7 +12,12 @@ stdenv.mkDerivation rec {
     sha1 = "bb8p58g88nkdcsj3h4acx7h925n2cy9g";
   };
 
-  buildInputs = [ wxGTK sqlite ];
+  preBuild = stdenv.lib.optionalString stdenv.isDarwin ''
+    cp build28/Info.plist.in build28/wxmac.icns build/
+  '';
+
+  buildInputs = [ wxGTK sqlite ]
+    ++ stdenv.lib.optionals stdenv.isDarwin [ darwin.apple_sdk.frameworks.Cocoa darwin.stubs.setfile darwin.stubs.rez darwin.stubs.derez ];
 
   meta = with stdenv.lib; {
     homepage = http://utelle.github.io/wxsqlite3/ ;
diff --git a/pkgs/development/tools/misc/cwebbin/default.nix b/pkgs/development/tools/misc/cwebbin/default.nix
index 75a06291b02..a952475b967 100644
--- a/pkgs/development/tools/misc/cwebbin/default.nix
+++ b/pkgs/development/tools/misc/cwebbin/default.nix
@@ -7,12 +7,12 @@ stdenv.mkDerivation rec {
   src = fetchFromGitHub {
     owner = "ascherer";
     repo = "cwebbin";
-    rev = name;
+    rev = "2016-05-20-22p";
     sha256 = "0zf93016hm9i74i2v384rwzcw16y3hg5vc2mibzkx1rzvqa50yfr";
   };
 
   cweb = fetchurl {
-    url = https://www.ctan.org/tex-archive/web/c_cpp/cweb/cweb.tar.gz;
+    url = https://www.ctan.org/tex-archive/web/c_cpp/cweb/cweb-3.64ah.tgz;
     sha256 = "1hdzxfzaibnjxjzgp6d2zay8nsarnfy9hfq55hz1bxzzl23n35aj";
   };
 
@@ -27,6 +27,7 @@ stdenv.mkDerivation rec {
     "CP=cp"
     "RM=rm"
     "PDFTEX=echo"
+    "CC=c++"
   ];
 
   buildPhase = ''
diff --git a/pkgs/games/exult/default.nix b/pkgs/games/exult/default.nix
index 27ffcf2e742..649d69c6fe6 100644
--- a/pkgs/games/exult/default.nix
+++ b/pkgs/games/exult/default.nix
@@ -30,6 +30,8 @@ stdenv.mkDerivation rec {
 
   enableParallelBuilding = true;
 
+  makeFlags = [ "DESTDIR=$(out)" ];
+
   postInstall =
     ''
       mkdir -p $out/share/exult/music
diff --git a/pkgs/os-specific/linux/sysdig/default.nix b/pkgs/os-specific/linux/sysdig/default.nix
index b23da5451d1..27a0d301acf 100644
--- a/pkgs/os-specific/linux/sysdig/default.nix
+++ b/pkgs/os-specific/linux/sysdig/default.nix
@@ -44,7 +44,7 @@ stdenv.mkDerivation rec {
     stdenv.cc.cc
   ];
 
-  postInstall = ''
+  postInstall = optionalString (!stdenv.isDarwin) ''
     patchelf --set-rpath "$libPath" "$out/bin/sysdig"
     patchelf --set-rpath "$libPath" "$out/bin/csysdig"
   '' + optionalString (kernel != null) ''
diff --git a/pkgs/tools/compression/zstdmt/default.nix b/pkgs/tools/compression/zstdmt/default.nix
index 14dd4f21b2d..5cf88e68c64 100644
--- a/pkgs/tools/compression/zstdmt/default.nix
+++ b/pkgs/tools/compression/zstdmt/default.nix
@@ -17,9 +17,7 @@ stdenv.mkDerivation rec {
     zstd lz4
   ];
 
-  buildPhase = ''
-    make zstdmt lz4mt
-  '';
+  makeFlags = [ "CC=cc" "zstdmt" "lz4mt" ];
 
   installPhase = ''
     mkdir -p $out/bin/
diff --git a/pkgs/tools/misc/rrdtool/default.nix b/pkgs/tools/misc/rrdtool/default.nix
index de4c97731ef..3d2666add42 100644
--- a/pkgs/tools/misc/rrdtool/default.nix
+++ b/pkgs/tools/misc/rrdtool/default.nix
@@ -1,5 +1,5 @@
 { fetchurl, stdenv, gettext, perl, pkgconfig, libxml2, pango, cairo, groff
-, tcl-8_5 }:
+, tcl-8_5, darwin }:
 
 stdenv.mkDerivation rec {
   name = "rrdtool-1.6.0";
@@ -12,7 +12,7 @@ stdenv.mkDerivation rec {
   nativeBuildInputs = [ pkgconfig ];
 
   buildInputs = [ gettext perl libxml2 pango cairo groff ]
-    ++ stdenv.lib.optional stdenv.isDarwin tcl-8_5;
+    ++ stdenv.lib.optionals stdenv.isDarwin [ tcl-8_5 darwin.apple_sdk.frameworks.ApplicationServices ];
 
   postInstall = ''
     # for munin and rrdtool support
diff --git a/pkgs/tools/networking/nuttcp/default.nix b/pkgs/tools/networking/nuttcp/default.nix
index 70f3d7e9c70..23cce602875 100644
--- a/pkgs/tools/networking/nuttcp/default.nix
+++ b/pkgs/tools/networking/nuttcp/default.nix
@@ -21,7 +21,7 @@ stdenv.mkDerivation rec {
   unpackPhase = ":";
 
   buildPhase = ''
-    gcc -O2 -o nuttcp $src
+    cc -O2 -o nuttcp $src
   '';
 
   installPhase = ''
diff --git a/pkgs/tools/typesetting/lout/builder.sh b/pkgs/tools/typesetting/lout/builder.sh
index ec52adc225b..cd3b9c67e3c 100755
--- a/pkgs/tools/typesetting/lout/builder.sh
+++ b/pkgs/tools/typesetting/lout/builder.sh
@@ -39,6 +39,6 @@ cat makefile |									\
   > "$nixMakefile" &&								\
 mkdir -p "$out/bin" && mkdir -p "$out/lib"					\
 mkdir -p "$out/man" && mkdir -p "$out/doc/lout" &&				\
-make -f "$nixMakefile" install installman &&					\
+make -f "$nixMakefile" CC=cc install installman &&					\
 installDoc &&									\
 fixupPhase