diff --git a/pkgs/applications/editors/emacs/default.nix b/pkgs/applications/editors/emacs/default.nix
index 570dc28c684..b88aa00d42d 100644
--- a/pkgs/applications/editors/emacs/default.nix
+++ b/pkgs/applications/editors/emacs/default.nix
@@ -2,6 +2,8 @@
 , Xaw3d, libXcursor,  pkgconfig, gettext, libXft, dbus, libpng, libjpeg, libungif
 , libtiff, librsvg, gconf, libxml2, imagemagick, gnutls, libselinux
 , alsaLib, cairo, acl, gpm, AppKit, GSS, ImageIO, m17n_lib, libotf
+, jansson, harfbuzz
+, libgccjit, targetPlatform, binutils, binutils-unwrapped, makeWrapper # native-comp params
 , systemd ? null
 , withX ? !stdenv.isDarwin
 , withNS ? stdenv.isDarwin
@@ -11,6 +13,7 @@
 , withCsrc ? true
 , srcRepo ? false, autoconf ? null, automake ? null, texinfo ? null
 , siteStart ? ./site-start.el
+, nativeComp ? false
 , toolkit ? (
   if withGTK2 then "gtk2"
   else if withGTK3 then "gtk3"
@@ -28,10 +31,13 @@ assert withGTK3 -> !withGTK2 && gtk3-x11 != null;
 assert withXwidgets -> withGTK3 && webkitgtk != null;
 
 
-stdenv.mkDerivation rec {
-  name = "emacs-${version}${versionModifier}";
+let
   version = "26.3";
   versionModifier = "";
+  name = "emacs-${version}${versionModifier}";
+
+in stdenv.mkDerivation {
+  inherit name version;
 
   src = fetchurl {
     url = "mirror://gnu/emacs/${name}.tar.xz";
@@ -50,29 +56,50 @@ stdenv.mkDerivation rec {
     })
   ];
 
-  postPatch = lib.optionalString srcRepo ''
-    rm -fr .git
-  '';
+  postPatch = lib.concatStringsSep "\n" [
+    (lib.optionalString srcRepo ''
+      rm -fr .git
+    '')
+
+    # Make native compilation work both inside and outside of nix build
+    (lib.optionalString nativeComp (let
+      libPath = lib.concatStringsSep ":" [
+        "${lib.getLib libgccjit}/lib/gcc/${targetPlatform.config}/${libgccjit.version}"
+        "${lib.getLib stdenv.cc.cc}/lib"
+        "${lib.getLib stdenv.glibc}/lib"
+      ];
+    in ''
+      substituteInPlace lisp/emacs-lisp/comp.el --replace \
+        "(defcustom comp-async-env-modifier-form nil" \
+        "(defcustom comp-async-env-modifier-form '((setenv \"LIBRARY_PATH\" (string-join (seq-filter (lambda (v) (null (eq v nil))) (list (getenv \"LIBRARY_PATH\") \"${libPath}\")) \":\")))"
+
+    ''))
+
+    ""
+  ];
 
   CFLAGS = "-DMAC_OS_X_VERSION_MAX_ALLOWED=101200";
 
-  nativeBuildInputs = [ pkgconfig ]
+  LIBRARY_PATH = if nativeComp then "${lib.getLib stdenv.cc.libc}/lib" else "";
+
+  nativeBuildInputs = [ pkgconfig makeWrapper ]
     ++ lib.optionals srcRepo [ autoconf automake texinfo ]
     ++ lib.optional (withX && (withGTK3 || withXwidgets)) wrapGAppsHook;
 
   buildInputs =
-    [ ncurses gconf libxml2 gnutls alsaLib acl gpm gettext ]
+    [ ncurses gconf libxml2 gnutls alsaLib acl gpm gettext jansson harfbuzz.dev ]
     ++ lib.optionals stdenv.isLinux [ dbus libselinux systemd ]
     ++ lib.optionals withX
       [ xlibsWrapper libXaw Xaw3d libXpm libpng libjpeg libungif libtiff libXft
-        gconf ]
+        gconf cairo ]
     ++ lib.optionals (withX || withNS) [ imagemagick librsvg ]
     ++ lib.optionals (stdenv.isLinux && withX) [ m17n_lib libotf ]
     ++ lib.optional (withX && withGTK2) gtk2-x11
     ++ lib.optionals (withX && withGTK3) [ gtk3-x11 gsettings-desktop-schemas ]
-    ++ lib.optional (stdenv.isDarwin && withX) cairo
     ++ lib.optionals (withX && withXwidgets) [ webkitgtk glib-networking ]
-    ++ lib.optionals withNS [ AppKit GSS ImageIO ];
+    ++ lib.optionals withNS [ AppKit GSS ImageIO ]
+    ++ lib.optionals nativeComp [ libgccjit ]
+    ;
 
   hardeningDisable = [ "format" ];
 
@@ -88,7 +115,9 @@ stdenv.mkDerivation rec {
       then [ "--with-x-toolkit=${toolkit}" "--with-xft" ]
       else [ "--with-x=no" "--with-xpm=no" "--with-jpeg=no" "--with-png=no"
              "--with-gif=no" "--with-tiff=no" ])
-    ++ lib.optional withXwidgets "--with-xwidgets";
+    ++ lib.optional withXwidgets "--with-xwidgets"
+    ++ lib.optional nativeComp "--with-nativecomp"
+    ;
 
   preConfigure = lib.optionalString srcRepo ''
     ./autogen.sh
@@ -106,13 +135,16 @@ stdenv.mkDerivation rec {
   postInstall = ''
     mkdir -p $out/share/emacs/site-lisp
     cp ${siteStart} $out/share/emacs/site-lisp/site-start.el
+
     $out/bin/emacs --batch -f batch-byte-compile $out/share/emacs/site-lisp/site-start.el
 
+    siteVersionDir=`ls $out/share/emacs | grep -v site-lisp | head -n 1`
+
     rm -rf $out/var
-    rm -rf $out/share/emacs/${version}/site-lisp
+    rm -rf $siteVersionDir
   '' + lib.optionalString withCsrc ''
     for srcdir in src lisp lwlib ; do
-      dstdir=$out/share/emacs/${version}/$srcdir
+      dstdir=$siteVersionDir/$srcdir
       mkdir -p $dstdir
       find $srcdir -name "*.[chm]" -exec cp {} $dstdir \;
       cp $srcdir/TAGS $dstdir
@@ -123,16 +155,24 @@ stdenv.mkDerivation rec {
     mv nextstep/Emacs.app $out/Applications
   '';
 
-  postFixup =
-    let libPath = lib.makeLibraryPath [
-      libXcursor
-    ];
-    in lib.optionalString (stdenv.isLinux && withX && toolkit == "lucid") ''
+  postFixup = lib.concatStringsSep "\n" [
+
+    (lib.optionalString (stdenv.isLinux && withX && toolkit == "lucid") ''
       patchelf --set-rpath \
-        "$(patchelf --print-rpath "$out/bin/emacs"):${libPath}" \
+        "$(patchelf --print-rpath "$out/bin/emacs"):${lib.makeLibraryPath [ libXcursor ]}" \
         "$out/bin/emacs"
       patchelf --add-needed "libXcursor.so.1" "$out/bin/emacs"
-    '';
+    '')
+
+    (lib.optionalString nativeComp ''
+      wrapProgram $out/bin/emacs-* --prefix PATH : "${lib.makeBinPath [ binutils binutils-unwrapped ]}"
+    '')
+
+  ];
+
+  passthru = {
+    inherit nativeComp;
+  };
 
   meta = with stdenv.lib; {
     description = "The extensible, customizable GNU text editor";
diff --git a/pkgs/build-support/emacs/generic.nix b/pkgs/build-support/emacs/generic.nix
index 6fa27f09839..956787ad59e 100644
--- a/pkgs/build-support/emacs/generic.nix
+++ b/pkgs/build-support/emacs/generic.nix
@@ -56,6 +56,16 @@ stdenv.mkDerivation ({
   meta = defaultMeta // meta;
 }
 
+// lib.optionalAttrs (emacs.nativeComp or false) {
+
+  LIBRARY_PATH = "${lib.getLib stdenv.cc.libc}/lib";
+
+  postInstall = ''
+    find $out/share/emacs -type f -name '*.el' -print0 | xargs -0 -n 1 -I {} -P $NIX_BUILD_CORES sh -c "emacs --batch -f batch-native-compile {} || true"
+  '';
+
+}
+
 // removeAttrs args [ "buildInputs" "packageRequires"
                       "meta"
                     ])