diff --git a/pkgs/development/libraries/jemalloc/default.nix b/pkgs/development/libraries/jemalloc/default.nix
index 8c8c181409d..d11ec0a7823 100644
--- a/pkgs/development/libraries/jemalloc/default.nix
+++ b/pkgs/development/libraries/jemalloc/default.nix
@@ -2,21 +2,23 @@
 
 stdenv.mkDerivation rec {
   name = "jemalloc-${version}";
-  version = "4.5.0";
+  version = "5.0.1";
 
   src = fetchurl {
     url = "https://github.com/jemalloc/jemalloc/releases/download/${version}/${name}.tar.bz2";
-    sha256 = "9409d85664b4f135b77518b0b118c549009dc10f6cba14557d170476611f6780";
+    sha256 = "4814781d395b0ef093b21a08e8e6e0bd3dab8762f9935bbfb71679b0dea7c3e9";
   };
 
   # By default, jemalloc puts a je_ prefix onto all its symbols on OSX, which
   # then stops downstream builds (mariadb in particular) from detecting it. This
   # option should remove the prefix and give us a working jemalloc.
-  configureFlags = stdenv.lib.optional stdenv.isDarwin "--with-jemalloc-prefix=";
-
+  configureFlags = stdenv.lib.optional stdenv.isDarwin "--with-jemalloc-prefix="
+                   # jemalloc is unable to correctly detect transparent hugepage support on
+                   # ARM (https://github.com/jemalloc/jemalloc/issues/526), and the default
+                   # kernel ARMv6/7 kernel does not enable it, so we explicitly disable support
+                   ++ stdenv.lib.optional stdenv.isArm "--disable-thp";
   doCheck = true;
 
-
   meta = with stdenv.lib; {
     homepage = http://jemalloc.net;
     description = "General purpose malloc(3) implementation";