diff --git a/nixos/modules/services/networking/nat.nix b/nixos/modules/services/networking/nat.nix
index 5681bda51cb..c80db8472f0 100644
--- a/nixos/modules/services/networking/nat.nix
+++ b/nixos/modules/services/networking/nat.nix
@@ -13,20 +13,24 @@ let
   dest = if cfg.externalIP == null then "-j MASQUERADE" else "-j SNAT --to-source ${cfg.externalIP}";
 
   flushNat = ''
-    iptables -w -t nat -D PREROUTING -j nixos-nat-pre 2>/dev/null|| true
-    iptables -w -t nat -F nixos-nat-pre 2>/dev/null || true
-    iptables -w -t nat -X nixos-nat-pre 2>/dev/null || true
-    iptables -w -t nat -D POSTROUTING -j nixos-nat-post 2>/dev/null || true
-    iptables -w -t nat -F nixos-nat-post 2>/dev/null || true
-    iptables -w -t nat -X nixos-nat-post 2>/dev/null || true
+    ip46tables -w -t nat -D PREROUTING -j nixos-nat-pre 2>/dev/null|| true
+    ip46tables -w -t nat -F nixos-nat-pre 2>/dev/null || true
+    ip46tables -w -t nat -X nixos-nat-pre 2>/dev/null || true
+    ip46tables -w -t nat -D POSTROUTING -j nixos-nat-post 2>/dev/null || true
+    ip46tables -w -t nat -F nixos-nat-post 2>/dev/null || true
+    ip46tables -w -t nat -X nixos-nat-post 2>/dev/null || true
+    ip46tables -w -t nat -D OUTPUT -j nixos-nat-out 2>/dev/null || true
+    ip46tables -w -t nat -F nixos-nat-out 2>/dev/null || true
+    ip46tables -w -t nat -X nixos-nat-out 2>/dev/null || true
 
     ${cfg.extraStopCommands}
   '';
 
   setupNat = ''
     # Create subchain where we store rules
-    iptables -w -t nat -N nixos-nat-pre
-    iptables -w -t nat -N nixos-nat-post
+    ip46tables -w -t nat -N nixos-nat-pre
+    ip46tables -w -t nat -N nixos-nat-post
+    ip46tables -w -t nat -N nixos-nat-out
 
     # We can't match on incoming interface in POSTROUTING, so
     # mark packets coming from the internal interfaces.
@@ -88,8 +92,9 @@ let
     ${cfg.extraCommands}
 
     # Append our chains to the nat tables
-    iptables -w -t nat -A PREROUTING -j nixos-nat-pre
-    iptables -w -t nat -A POSTROUTING -j nixos-nat-post
+    ip46tables -w -t nat -A PREROUTING -j nixos-nat-pre
+    ip46tables -w -t nat -A POSTROUTING -j nixos-nat-post
+    ip46tables -w -t nat -A OUTPUT -j nixos-nat-out
   '';
 
 in