diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index ce04004a9db..711f1989407 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -2480,7 +2480,7 @@ let
     inherit noSysDirs;
 
     # PGO seems to speed up compilation by gcc by ~10%, see #445 discussion
-    profiledCompiler = with stdenv; (isi686 || isx86_64);
+    profiledCompiler = with stdenv; (!isDarwin && (isi686 || isx86_64));
 
     # When building `gcc.crossDrv' (a "Canadian cross", with host == target
     # and host != build), `cross' must be null but the cross-libc must still