diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 9cdd9c0d074..b14043a8349 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -5982,6 +5982,7 @@ rec {
 
   psycopg2 = buildPythonPackage rec {
     name = "psycopg2-2.5.3";
+    disabled = isPyPy;
 
     # error: invalid command 'test'
     doCheck = false;