diff --git a/pkgs/development/python-modules/cbor2/default.nix b/pkgs/development/python-modules/cbor2/default.nix
index f793ecfae37..776cc4d38e9 100644
--- a/pkgs/development/python-modules/cbor2/default.nix
+++ b/pkgs/development/python-modules/cbor2/default.nix
@@ -1,4 +1,5 @@
 { lib
+, stdenv
 , buildPythonPackage
 , fetchPypi
 , pytestCheckHook
@@ -22,6 +23,12 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
+  # https://github.com/agronholm/cbor2/issues/99
+  disabledTests = lib.optionals stdenv.is32bit [
+    "test_huge_truncated_bytes"
+    "test_huge_truncated_string"
+  ];
+
   pythonImportsCheck = [ "cbor2" ];
 
   meta = with lib; {