diff --git a/pkgs/development/python-modules/python-telegram-bot/default.nix b/pkgs/development/python-modules/python-telegram-bot/default.nix
new file mode 100644
index 00000000000..d5547217910
--- /dev/null
+++ b/pkgs/development/python-modules/python-telegram-bot/default.nix
@@ -0,0 +1,31 @@
+{ stdenv, fetchPypi, buildPythonPackage, certifi, future, urllib3 }:
+
+buildPythonPackage rec {
+  pname = "python-telegram-bot";
+  version = "9.0.0";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "0a5b4wfc6ms7kblynw2h3ygpww98kyz5n8iibqbdyykwx8xj7hzm";
+  };
+
+  prePatch = ''
+    rm -rf telegram/vendor
+    substituteInPlace telegram/utils/request.py \
+      --replace "import telegram.vendor.ptb_urllib3.urllib3 as urllib3" "import urllib3 as urllib3" \
+      --replace "import telegram.vendor.ptb_urllib3.urllib3.contrib.appengine as appengine" "import urllib3.contrib.appengine as appengine" \
+      --replace "from telegram.vendor.ptb_urllib3.urllib3.connection import HTTPConnection" "from urllib3.connection import HTTPConnection" \
+      --replace "from telegram.vendor.ptb_urllib3.urllib3.util.timeout import Timeout" "from urllib3.util.timeout import Timeout"
+  '';
+
+  propagatedBuildInputs = [ certifi future urllib3 ];
+
+  doCheck = false;
+
+  meta = with stdenv.lib; {
+    description = "This library provides a pure Python interface for the Telegram Bot API.";
+    homepage = https://python-telegram-bot.org;
+    license = licenses.lgpl3;
+    maintainers = with maintainers; [ veprbl ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index dae1db07f06..50b964af6ef 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -21521,6 +21521,8 @@ EOF
     };
   };
 
+  python-telegram-bot = callPackage ../development/python-modules/python-telegram-bot { };
+
   irc = buildPythonPackage rec {
     name = "irc-${version}";
     version = "14.2.2";