diff --git a/pkgs/development/python-modules/biopython/default.nix b/pkgs/development/python-modules/biopython/default.nix
index 773d8193cb0..f96b8447e8a 100644
--- a/pkgs/development/python-modules/biopython/default.nix
+++ b/pkgs/development/python-modules/biopython/default.nix
@@ -2,6 +2,7 @@
 , buildPythonPackage
 , fetchPypi
 , numpy
+, isPy3k
 }:
 
 buildPythonPackage rec {
@@ -13,6 +14,8 @@ buildPythonPackage rec {
     sha256 = "fb1936e9ca9e7af8de1050e84375f23328e04b801063edf0ad73733494d8ec42";
   };
 
+  disabled = !isPy3k;
+
   propagatedBuildInputs = [ numpy ];
   # Checks try to write to $HOME, which does not work with nix
   doCheck = false;