diff --git a/pkgs/development/python-modules/numcodecs/default.nix b/pkgs/development/python-modules/numcodecs/default.nix
new file mode 100644
index 00000000000..775cfeded8b
--- /dev/null
+++ b/pkgs/development/python-modules/numcodecs/default.nix
@@ -0,0 +1,45 @@
+{ lib
+, buildPythonPackage
+, fetchPypi
+, setuptools_scm
+, cython
+, numpy
+, msgpack
+, pytest
+, python
+}:
+
+buildPythonPackage rec {
+  pname = "numcodecs";
+  version = "0.6.3";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "086qwlyi01rpgyyyy8bmhh9i7hpksyz33ldci3wdwmhiblyl362y";
+  };
+
+  nativeBuildInputs = [
+    setuptools_scm
+    cython
+  ];
+
+  propagatedBuildInputs = [
+    numpy
+    msgpack
+  ];
+
+  checkInputs = [
+    pytest
+  ];
+
+  checkPhase = ''
+    pytest $out/${python.sitePackages}/numcodecs -k "not test_backwards_compatibility"
+  '';
+
+  meta = with lib;{
+    homepage = https://github.com/alimanfoo/numcodecs;
+    license = licenses.mit;
+    description = "Buffer compression and transformation codecs for use in data storage and communication applications";
+    maintainers = [ maintainers.costrouc ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 2cc3e62d2da..5254d04ceac 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -3816,6 +3816,8 @@ in {
 
   numba = callPackage ../development/python-modules/numba { };
 
+  numcodecs = callPackage ../development/python-modules/numcodecs { };
+
   numexpr = callPackage ../development/python-modules/numexpr { };
 
   Nuitka = callPackage ../development/python-modules/nuitka { };