diff --git a/pkgs/development/python-modules/qtpy/default.nix b/pkgs/development/python-modules/qtpy/default.nix
new file mode 100644
index 00000000000..035ea32b398
--- /dev/null
+++ b/pkgs/development/python-modules/qtpy/default.nix
@@ -0,0 +1,25 @@
+{ stdenv, buildPythonPackage, fetchPypi, pyside, pytest }:
+
+buildPythonPackage rec {
+  pname = "QtPy";
+  version = "1.3.1";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "04skhjb2dbbhvpq0x71nnz2h68805fkxfpkdjhwvd7lzsljjbbq8";
+  };
+
+  # no concrete propagatedBuildInputs as multiple backends are supposed
+  checkInputs = [ pyside pytest ];
+
+  doCheck = false; # require X
+  checkPhase = ''
+    py.test qtpy/tests
+  '';
+
+  meta = with stdenv.lib; {
+    description = "Abstraction layer for PyQt5/PyQt4/PySide2/PySide";
+    homepage = https://github.com/spyder-ide/qtpy;
+    license = licenses.mit;
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 5557d0f3531..afd11848f9b 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -17126,6 +17126,8 @@ in {
 
   qtconsole = callPackage ../development/python-modules/qtconsole { };
 
+  qtpy = callPackage ../development/python-modules/qtpy { };
+
   quantities = buildPythonPackage rec {
     name = "quantities-0.10.1";