diff --git a/pkgs/development/python-modules/python-telegram-bot/default.nix b/pkgs/development/python-modules/python-telegram-bot/default.nix
index 30caa0f3d6a..f36f8239568 100644
--- a/pkgs/development/python-modules/python-telegram-bot/default.nix
+++ b/pkgs/development/python-modules/python-telegram-bot/default.nix
@@ -23,7 +23,11 @@ buildPythonPackage rec {
   checkInputs = [ pytest ];
   propagatedBuildInputs = [ certifi future urllib3 tornado decorator ];
 
-  pipInstallFlags = "--install-option '--with-upstream-urllib3'";
+  # --with-upstream-urllib3 is not working properly
+  postPatch = ''
+    rm -rf telegram/vendor
+  '';
+  setupPyGlobalFlags = "--with-upstream-urllib3";
 
   # tests not included with release
   doCheck = false;