diff --git a/pkgs/development/python-modules/pyspread/default.nix b/pkgs/development/python-modules/pyspread/default.nix
new file mode 100644
index 00000000000..2f275005c19
--- /dev/null
+++ b/pkgs/development/python-modules/pyspread/default.nix
@@ -0,0 +1,57 @@
+{ buildPythonPackage
+, fetchPypi
+, isPy3k
+, stdenv
+, numpy
+, wxPython
+, matplotlib
+, pycairo
+, python-gnupg
+, xlrd
+, xlwt
+, jedi
+, pyenchant
+, basemap
+, pygtk
+, makeDesktopItem
+}:
+
+buildPythonPackage rec {
+  name = "${pname}-${version}";
+  pname = "pyspread";
+  version = "1.1";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "0m1a4zvzrfrnc42j8mrbm7747w03nzyl9z02wjagccmlhi6nd9hx";
+  };
+
+  propagatedBuildInputs = [ numpy wxPython matplotlib pycairo python-gnupg xlrd xlwt jedi pyenchant basemap pygtk ];
+  # Could also (optionally) add pyrsvg and python bindings for libvlc
+
+  # Tests try to access X Display
+  doCheck = false;
+
+  disabled = isPy3k;
+
+  desktopItem = makeDesktopItem rec {
+    name = pname;
+    exec = name;
+    icon = name;
+    desktopName = "Pyspread";
+    genericName = "Spreadsheet";
+    comment = meta.description;
+    categories = "Development;Spreadsheet;";
+  };
+
+  postInstall = ''
+    mkdir -p $out/share/applications
+    cp $desktopItem/share/applications/* $out/share/applications
+  '';
+
+  meta = with stdenv.lib; {
+    description = "Pyspread is a non-traditional spreadsheet application that is based on and written in the programming language Python";
+    homepage = https://manns.github.io/pyspread/;
+    license = licenses.gpl3;
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index e2a615e7a0f..355d470ca5d 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -20558,6 +20558,8 @@ in {
     };
   };
 
+  pyspread = callPackage ../development/python-modules/pyspread { };
+
   pyx = buildPythonPackage rec {
     name = "pyx-${version}";
     version = "0.14.1";