diff --git a/pkgs/development/tools/analysis/valgrind/callgrind_annotate.patch b/pkgs/development/tools/analysis/valgrind/callgrind_annotate.patch
new file mode 100644
index 00000000000..7b09ead4510
--- /dev/null
+++ b/pkgs/development/tools/analysis/valgrind/callgrind_annotate.patch
@@ -0,0 +1,8 @@
+--- valgrind-3.3.0/callgrind/callgrind_annotate.in	2007-12-11 00:18:11.000000000 +0100
++++ valgrind-3.3.0/callgrind/callgrind_annotate.in	2008-06-03 23:12:26.000000000 +0200
+@@ -1,4 +1,4 @@
+-#! /usr/bin/perl -w
++#! @PERL@ -w
+ ##--------------------------------------------------------------------##
+ ##--- The cache simulation framework: instrumentation, recording   ---##
+ ##--- and results printing.                                        ---##
diff --git a/pkgs/development/tools/analysis/valgrind/default.nix b/pkgs/development/tools/analysis/valgrind/default.nix
index 05ba5d75894..995cb48313c 100644
--- a/pkgs/development/tools/analysis/valgrind/default.nix
+++ b/pkgs/development/tools/analysis/valgrind/default.nix
@@ -8,6 +8,8 @@ stdenv.mkDerivation {
     sha256 = "0yllx5a2f5bx18gqz74aikr27zxwpblswn65lqvm9rbzswlq5w2s";
   };
 
+  patches = [ ./callgrind_annotate.patch ];
+
   # Perl is needed for `cg_annotate'.
   # GDB is needed to provide a sane default for `--db-command'.
   buildInputs = [ perl gdb ];