diff --git a/pkgs/development/python-modules/pyside2/default.nix b/pkgs/development/python-modules/pyside2/default.nix
new file mode 100644
index 00000000000..afa48569e2a
--- /dev/null
+++ b/pkgs/development/python-modules/pyside2/default.nix
@@ -0,0 +1,38 @@
+{ buildPythonPackage, python, fetchurl, stdenv,
+  cmake, ninja, qt5, shiboken2 }:
+
+stdenv.mkDerivation rec {
+  pname = "pyside2";
+  version = "5.12.3";
+
+  src = fetchurl {
+    url = "https://download.qt.io/official_releases/QtForPython/pyside2/PySide2-${version}-src/pyside-setup-everywhere-src-${version}.tar.xz";
+    sha256 = "0hk89jm8pa0q6kifask5rrffa3bvx02dg2f97ibv7wds9dysnyjg";
+  };
+
+  patches = [
+    ./dont_ignore_optional_modules.patch
+  ];
+
+  postPatch = ''
+    cd sources/pyside2
+  '';
+
+  cmakeFlags = [
+    "-DBUILD_TESTS=OFF"
+    "-DPYTHON_EXECUTABLE=${python.interpreter}"
+  ];
+
+  nativeBuildInputs = [ cmake ninja qt5.qmake shiboken2 python ];
+  buildInputs = with qt5; [
+    qtbase qtxmlpatterns qtmultimedia qttools qtx11extras qtlocation qtscript
+    qtwebsockets qtwebengine qtwebchannel qtcharts qtsensors qtsvg
+  ];
+
+  meta = with stdenv.lib; {
+    description = "LGPL-licensed Python bindings for Qt";
+    license = licenses.lgpl21;
+    homepage = "https://wiki.qt.io/Qt_for_Python";
+    maintainers = with maintainers; [ gebner ];
+  };
+}
diff --git a/pkgs/development/python-modules/pyside2/dont_ignore_optional_modules.patch b/pkgs/development/python-modules/pyside2/dont_ignore_optional_modules.patch
new file mode 100644
index 00000000000..681e16a2bfd
--- /dev/null
+++ b/pkgs/development/python-modules/pyside2/dont_ignore_optional_modules.patch
@@ -0,0 +1,11 @@
+--- pyside-setup-everywhere-src-5.12.3/sources/pyside2/CMakeLists.txt~	2019-06-15 19:07:48.368704430 +0200
++++ pyside-setup-everywhere-src-5.12.3/sources/pyside2/CMakeLists.txt	2019-06-15 19:08:04.429489908 +0200
+@@ -219,7 +219,7 @@
+     # If the module was found, and also the module path is the same as the
+     # Qt5Core base path, we will generate the list with the modules to be installed
+     set(looked_in_message ". Looked in: ${${_name_dir}}")
+-    if("${${_name_found}}" AND (("${found_basepath}" GREATER "0") OR ("${found_basepath}" EQUAL "0")))
++    if("${${_name_found}}")
+         message(STATUS "${module_state} module ${name} found (${ARGN})${looked_in_message}")
+         # record the shortnames for the tests
+         list(APPEND all_module_shortnames ${shortname})
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 7a331ad7914..4ab6261c229 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -801,6 +801,10 @@ in {
 
   pysideTools = callPackage ../development/python-modules/pyside/tools.nix { };
 
+  pyside2 = toPythonModule (callPackage ../development/python-modules/pyside2 {
+    inherit (pkgs) cmake qt5 ninja;
+  });
+
   shiboken2 = toPythonModule (callPackage ../development/python-modules/shiboken2 {
     inherit (pkgs) cmake qt5 llvmPackages;
   });