diff --git a/pkgs/applications/science/robotics/mavproxy/default.nix b/pkgs/applications/science/robotics/mavproxy/default.nix
index 8e7c5bddd96..22a32f89bde 100644
--- a/pkgs/applications/science/robotics/mavproxy/default.nix
+++ b/pkgs/applications/science/robotics/mavproxy/default.nix
@@ -1,5 +1,5 @@
-{ lib, buildPythonApplication, fetchPypi, matplotlib, numpy, pymavlink, pyserial
-, setuptools, wxPython_4_0 }:
+{ stdenv, lib, buildPythonApplication, fetchPypi, matplotlib, numpy, pymavlink, pyserial
+, setuptools, wxPython_4_0, billiard, gnureadline }:
 
 buildPythonApplication rec {
   pname = "MAVProxy";
@@ -10,6 +10,11 @@ buildPythonApplication rec {
     sha256 = "fe046481b793b592334749249620fce8a463f4c46b394ff744645975465d677b";
   };
 
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace "opencv-python" ""
+  '';
+
   propagatedBuildInputs = [
     matplotlib
     numpy
@@ -17,7 +22,7 @@ buildPythonApplication rec {
     pyserial
     setuptools
     wxPython_4_0
-  ];
+  ] ++ lib.optionals stdenv.isDarwin [ billiard gnureadline ];
 
   # No tests
   doCheck = false;