diff --git a/pkgs/development/libraries/spice-gtk/default.nix b/pkgs/development/libraries/spice-gtk/default.nix
index bc583f732db..0169a42ed65 100644
--- a/pkgs/development/libraries/spice-gtk/default.nix
+++ b/pkgs/development/libraries/spice-gtk/default.nix
@@ -1,8 +1,39 @@
-{ stdenv, fetchurl, pkgconfig, spice-protocol, gettext, celt_0_5_1
-, openssl, libpulseaudio, pixman, gobject-introspection, libjpeg_turbo, zlib
-, cyrus_sasl, python2Packages, autoreconfHook, usbredir, libsoup
-, withPolkit ? true, polkit, acl, usbutils
-, vala, gtk3, epoxy, libdrm, gst_all_1, phodav, opusfile }:
+{ stdenv
+, fetchurl
+, pkgconfig
+, fetchpatch
+, meson
+, ninja
+, python3
+, spice-protocol
+, gettext
+, openssl
+, libpulseaudio
+, pixman
+, gobject-introspection
+, libjpeg_turbo
+, zlib
+, cyrus_sasl
+, usbredir
+, libsoup
+, polkit
+, acl
+, usbutils
+, vala
+, gtk3
+, epoxy
+, libdrm
+, gst_all_1
+, phodav
+, libopus
+, gtk-doc
+, json-glib
+, lz4
+, libcacard
+, perl
+, docbook_xsl
+, withPolkit ? true
+}:
 
 # If this package is built with polkit support (withPolkit=true),
 # usb redirection reqires spice-client-glib-usb-acl-helper to run setuid root.
@@ -25,18 +56,15 @@
 #    KERNEL=="*", SUBSYSTEMS=="usb", MODE="0664", GROUP="usb"
 #  '';
 
-with stdenv.lib;
+stdenv.mkDerivation rec {
+  pname = "spice-gtk";
+  version = "0.37";
 
-let
-  inherit (python2Packages) python pygtk;
-in stdenv.mkDerivation rec {
-  name = "spice-gtk-0.35";
-
-  outputs = [ "out" "dev" ];
+  outputs = [ "out" "dev" "devdoc" "man" ];
 
   src = fetchurl {
-    url = "https://www.spice-space.org/download/gtk/${name}.tar.bz2";
-    sha256 = "11lymg467gvj5ys8k22ihnfbxjn4x34ygyzirpg2nphjwlyhgrml";
+    url = "https://www.spice-space.org/download/gtk/${pname}-${version}.tar.bz2";
+    sha256 = "1drvj8y35gnxbnrxsipwi15yh0vs9ixzv4wslz6r3lra8w3bfa0z";
   };
 
   postPatch = ''
@@ -45,27 +73,50 @@ in stdenv.mkDerivation rec {
       --replace 'ACL_HELPER_PATH"/' '"'
   '';
 
-  buildInputs = [
-    spice-protocol celt_0_5_1 openssl libpulseaudio gst_all_1.gst-plugins-base pixman
-    libjpeg_turbo zlib cyrus_sasl python pygtk usbredir gtk3 epoxy libdrm phodav opusfile
-  ] ++ optionals withPolkit [ polkit acl usbutils ] ;
+  nativeBuildInputs = [
+    docbook_xsl
+    gettext
+    gobject-introspection
+    gtk-doc
+    libsoup
+    meson
+    ninja
+    perl
+    pkgconfig
+    python3
+    python3.pkgs.pyparsing
+    python3.pkgs.six
+    vala
+  ];
 
-  nativeBuildInputs = [ pkgconfig gettext libsoup autoreconfHook vala gobject-introspection ];
+  buildInputs = [
+    cyrus_sasl
+    epoxy
+    gst_all_1.gst-plugins-base
+    gtk3
+    json-glib
+    libcacard
+    libdrm
+    libjpeg_turbo
+    lz4
+    openssl
+    libopus
+    phodav
+    pixman
+    spice-protocol
+    usbredir
+    zlib
+  ] ++ stdenv.lib.optionals withPolkit [ polkit acl usbutils ] ;
 
   PKG_CONFIG_POLKIT_GOBJECT_1_POLICYDIR = "${placeholder "out"}/share/polkit-1/actions";
 
-  configureFlags = [
-    "--with-gtk3"
-    "--enable-introspection"
-    "--enable-vala"
-    "--enable-celt051"
+  mesonFlags = [
+    "-Dauto_features=enabled"
+    "-Dcelt051=disabled"
+    "-Dpulse=disabled" # is deprecated upstream
   ];
 
-  dontDisableStatic = true; # Needed by the coroutine test
-
-  enableParallelBuilding = true;
-
-  meta = {
+  meta = with stdenv.lib; {
     description = "A GTK+3 SPICE widget";
     longDescription = ''
       spice-gtk is a GTK+3 SPICE widget. It features glib-based
diff --git a/pkgs/development/libraries/spice-protocol/default.nix b/pkgs/development/libraries/spice-protocol/default.nix
index 18ec02b4acf..c32f336939c 100644
--- a/pkgs/development/libraries/spice-protocol/default.nix
+++ b/pkgs/development/libraries/spice-protocol/default.nix
@@ -1,11 +1,12 @@
 { stdenv, fetchurl }:
 
 stdenv.mkDerivation rec {
-  name = "spice-protocol-0.12.15";
+  pname = "spice-protocol";
+  version = "0.14.0";
 
   src = fetchurl {
-    url = "https://www.spice-space.org/download/releases/${name}.tar.bz2";
-    sha256 = "06b461i4jv741in8617jjpfk28wk7zs9p7841njkf4sbm8xv4kcb";
+    url = "https://www.spice-space.org/download/releases/${pname}-${version}.tar.bz2";
+    sha256 = "1b3f44c13pqsp7aabmcinfbmgl79038bp5548l5pjs16lcfam95n";
   };
 
   postInstall = ''
diff --git a/pkgs/development/libraries/spice/correct-meson.patch b/pkgs/development/libraries/spice/correct-meson.patch
new file mode 100644
index 00000000000..d3422cb915b
--- /dev/null
+++ b/pkgs/development/libraries/spice/correct-meson.patch
@@ -0,0 +1,26 @@
+diff --git a/meson.build b/meson.build
+index 8b8ae8bb..e58c436c 100644
+--- a/meson.build
++++ b/meson.build
+@@ -2,7 +2,7 @@
+ # project definition
+ #
+ project('spice', 'c',
+-        version : run_command('build-aux/git-version-gen', '${MESON_SOURCE_ROOT}/.tarball-version', check : true).stdout().strip(),
++        version : run_command('build-aux/git-version-gen', meson.source_root() + '/.tarball-version', check : true).stdout().strip(),
+         license : 'LGPLv2.1',
+         meson_version : '>= 0.48')
+
+diff --git a/server/meson.build b/server/meson.build
+index 34d8eef1..988ccab2 100644
+--- a/server/meson.build
++++ b/server/meson.build
+@@ -7,7 +7,7 @@ version_info = meson.project_version().split('.')
+ major = '@0@'.format(version_info[0])
+ minor = '@0@'.format(version_info[1])
+ micro = version_info[2].to_int()
+-if not version_info[3].contains('git')
++if not version_info.contains('git')
+   micro += 1
+ endif
+ micro = '@0@'.format(micro)
diff --git a/pkgs/development/libraries/spice/default.nix b/pkgs/development/libraries/spice/default.nix
index dadbe57dccd..902bc6a5560 100644
--- a/pkgs/development/libraries/spice/default.nix
+++ b/pkgs/development/libraries/spice/default.nix
@@ -1,38 +1,93 @@
-{ stdenv, fetchurl, pkgconfig, pixman, celt, alsaLib
-, openssl, libXrandr, libXfixes, libXext, libXrender, libXinerama
-, libjpeg, zlib, spice-protocol, python, pyparsing, glib, cyrus_sasl
-, libcacard, lz4 }:
-
-with stdenv.lib;
+{ stdenv
+, substituteAll
+, fetchurl
+, meson
+, ninja
+, pkgconfig
+, pixman
+, alsaLib
+, openssl
+, libXrandr
+, libXfixes
+, libXext
+, libXrender
+, libXinerama
+, libjpeg
+, zlib
+, spice-protocol
+, python3
+, glib
+, cyrus_sasl
+, libcacard
+, lz4
+, libopus
+, gst_all_1
+, orc
+}:
 
 stdenv.mkDerivation rec {
-  name = "spice-0.14.0";
+  pname = "spice";
+  version = "0.14.2";
 
   src = fetchurl {
-    url = "https://www.spice-space.org/download/releases/${name}.tar.bz2";
-    sha256 = "0j5q7cp5p95jk8fp48gz76rz96lifimdsx1wnpmfal0nnnar9nrs";
+    url = "https://www.spice-space.org/download/releases/${pname}-${version}.tar.bz2";
+    sha256 = "19r999py9v9c7md2bb8ysj809ag1hh6djl1ik8jcgx065s4b60xj";
   };
 
-  buildInputs = [ pixman celt alsaLib openssl libjpeg zlib
-                  libXrandr libXfixes libXrender libXext libXinerama
-                  python pyparsing glib cyrus_sasl libcacard lz4 ];
+  patches = [
+    # submitted https://gitlab.freedesktop.org/spice/spice/merge_requests/4
+    ./correct-meson.patch
+  ];
 
-  nativeBuildInputs = [ pkgconfig spice-protocol ];
+  postPatch = ''
+    patchShebangs build-aux
+  '';
+
+
+  nativeBuildInputs = [
+    meson
+    ninja
+    pkgconfig
+    spice-protocol
+    python3
+    python3.pkgs.six
+    python3.pkgs.pyparsing
+  ];
+
+  buildInputs = [
+    alsaLib
+    cyrus_sasl
+    glib
+    gst_all_1.gst-plugins-base
+    libXext
+    libXfixes
+    libXinerama
+    libXrandr
+    libXrender
+    libcacard
+    libjpeg
+    libopus
+    lz4
+    openssl
+    orc
+    pixman
+    python3.pkgs.pyparsing
+    zlib
+  ];
 
   NIX_CFLAGS_COMPILE = "-fno-stack-protector";
 
-  configureFlags = [
-    "--with-sasl"
-    "--enable-smartcard"
-    "--enable-client"
-    "--enable-lz4"
+  mesonFlags = [
+    "-Dauto_features=enabled"
+    "-Dgstreamer=1.0"
+    "-Dcelt051=disabled"
   ];
 
   postInstall = ''
     ln -s spice-server $out/include/spice
   '';
 
-  meta = {
+  meta = with stdenv.lib; {
     description = "Complete open source solution for interaction with virtualized desktop devices";
     longDescription = ''
       The Spice project aims to provide a complete open source solution for interaction
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 59b31d9405e..2153fa916e0 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -13175,10 +13175,7 @@ in
 
   sphinxsearch = callPackage ../servers/search/sphinxsearch { };
 
-  spice = callPackage ../development/libraries/spice {
-    celt = celt_0_5_1;
-    inherit (pythonPackages) pyparsing;
-  };
+  spice = callPackage ../development/libraries/spice { };
 
   spice-gtk = callPackage ../development/libraries/spice-gtk { };