diff --git a/pkgs/applications/misc/tthsum/default.nix b/pkgs/applications/misc/tthsum/default.nix
index 66bfcbcf4d9..dbac56abaa1 100644
--- a/pkgs/applications/misc/tthsum/default.nix
+++ b/pkgs/applications/misc/tthsum/default.nix
@@ -15,6 +15,8 @@ stdenv.mkDerivation rec {
     cp obj-unix/tthsum $out/bin
   '';
 
+  doCheck = !stdenv.isDarwin;
+
   meta = with stdenv.lib; {
     description = "An md5sum-alike program that works with Tiger/THEX hashes";
     longDescription = ''
diff --git a/pkgs/development/python-modules/papis/default.nix b/pkgs/development/python-modules/papis/default.nix
index d9be946900c..5a9934d6be6 100644
--- a/pkgs/development/python-modules/papis/default.nix
+++ b/pkgs/development/python-modules/papis/default.nix
@@ -5,6 +5,7 @@
 , prompt_toolkit, pygments
 #, optional, dependencies
 , jinja2, whoosh, pytest
+, stdenv
 }:
 
 buildPythonPackage rec {
@@ -28,6 +29,8 @@ buildPythonPackage rec {
     jinja2 whoosh
   ];
 
+  doCheck = !stdenv.isDarwin;
+
   checkInputs = ([
     pytest
   ]) ++ [
diff --git a/pkgs/development/python-modules/sqlalchemy-migrate/default.nix b/pkgs/development/python-modules/sqlalchemy-migrate/default.nix
index 9daf2a696c2..596f9e47a08 100644
--- a/pkgs/development/python-modules/sqlalchemy-migrate/default.nix
+++ b/pkgs/development/python-modules/sqlalchemy-migrate/default.nix
@@ -21,6 +21,8 @@ buildPythonPackage rec {
   checkInputs = [ unittest2 scripttest pytz mock testtools testrepository ];
   propagatedBuildInputs = [ pbr tempita decorator sqlalchemy six sqlparse ];
 
+  doCheck = !stdenv.isDarwin;
+
   prePatch = ''
     sed -i -e /tempest-lib/d \
            -e /testtools/d \
diff --git a/pkgs/development/python-modules/xlib/default.nix b/pkgs/development/python-modules/xlib/default.nix
index 0b0f60ea16e..1903c3aaca8 100644
--- a/pkgs/development/python-modules/xlib/default.nix
+++ b/pkgs/development/python-modules/xlib/default.nix
@@ -30,6 +30,8 @@ buildPythonPackage rec {
   buildInputs = [ xorg.libX11 ];
   propagatedBuildInputs = [ six ];
 
+  doCheck = !stdenv.isDarwin;
+
   meta = with stdenv.lib; {
     description = "Fully functional X client library for Python programs";
     homepage = http://python-xlib.sourceforge.net/;
diff --git a/pkgs/development/tools/build-managers/dub/default.nix b/pkgs/development/tools/build-managers/dub/default.nix
index 3f733e97eed..7b882926e1f 100644
--- a/pkgs/development/tools/build-managers/dub/default.nix
+++ b/pkgs/development/tools/build-managers/dub/default.nix
@@ -32,7 +32,7 @@ stdenv.mkDerivation rec {
     ./build.sh
   '';
 
-  doCheck = true;
+  doCheck = !stdenv.isDarwin;
 
   checkPhase = ''
     export DUB=$NIX_BUILD_TOP/source/bin/dub