diff --git a/pkgs/development/python-modules/virtualenv/default.nix b/pkgs/development/python-modules/virtualenv/default.nix
index 5d60f2bf39e..ec22660830b 100644
--- a/pkgs/development/python-modules/virtualenv/default.nix
+++ b/pkgs/development/python-modules/virtualenv/default.nix
@@ -75,6 +75,9 @@ buildPythonPackage rec {
   disabledTests = [
     "test_can_build_c_extensions"
     "test_xonsh" # imports xonsh, which is not in pythonPackages
+    # tests search `python3`, fail on python2, pypy
+    "test_python_via_env_var"
+    "test_python_multi_value_prefer_newline_via_env_var"
   ];
 
   pythonImportsCheck = [ "virtualenv" ];