diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index e63e0854021..be4a69ef7b0 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -14695,6 +14695,51 @@ in modules // {
     };
   };
 
+  Nuitka = let
+    # scons is needed but using it requires Python 2.7
+    # Therefore we create a separate env for it.
+    scons = pkgs.python27.withPackages(ps: [ pkgs.scons ]);
+  in buildPythonPackage rec {
+    version = "0.5.21.3";
+    name = "Nuitka-${version}";
+
+    # Latest version is not yet on PyPi
+    src = pkgs.fetchurl {
+      url = "https://github.com/kayhayen/Nuitka/archive/${version}.tar.gz";
+      sha256 = "1i2069hxb94q9kkwcbky59fin8hk1vlj90lwgmrdhn1srvig1cq3";
+    };
+
+    buildInputs = with self; stdenv.lib.optionals doCheck [ vmprof pyqt4 ];
+
+    propagatedBuildInputs = [ scons ];
+
+    postPatch = ''
+      patchShebangs tests/run-tests
+    '' + stdenv.lib.optionalString stdenv.isLinux ''
+      substituteInPlace nuitka/plugins/standard/ImplicitImports.py --replace 'locateDLL("uuid")' '"${pkgs.utillinux.out}/lib/libuuid.so"'
+    '';
+
+    # We do not want any wrappers here.
+    postFixup = '''';
+
+    checkPhase = ''
+      tests/run-tests
+    '';
+
+    # Problem with a subprocess (parts)
+    doCheck = false;
+
+    # Requires CPython
+    disabled = isPyPy;
+
+    meta = {
+      description = "Python compiler with full language support and CPython compatibility";
+      license = licenses.asl20;
+      homepage = http://nuitka.net/;
+    };
+  };
+
+
   buildNumpyPackage = callPackage ../development/python-modules/numpy.nix {
     gfortran = pkgs.gfortran;
     blas = pkgs.openblasCompat;
@@ -24324,6 +24369,29 @@ in modules // {
     };
   });
 
+  vmprof = buildPythonPackage rec {
+    version = "0.3.3";
+    name = "vmprof-${version}";
+
+    # Url using old scheme doesn't seem to work
+    src = pkgs.fetchurl {
+      url = "https://files.pythonhosted.org/packages/c3/f3/f039ca77e727c5c2d3e61967a2a5c9ecc0ef6ca235012fd5559febb77cd0/vmprof-0.3.3.tar.gz";
+      sha256 = "991bc2f1dc824c63e9b399f9e8606deded92a52378d0e449f258807d7556b039";
+    };
+
+    propagatedBuildInputs = with self; [ requests2 six];
+
+    # No tests included
+    doCheck = false;
+
+    meta = {
+      description = "A vmprof client";
+      license = licenses.mit;
+      homepage = https://vmprof.readthedocs.org/;
+    };
+
+  };
+
   vultr = buildPythonPackage rec {
     version = "0.1.2";
     name = "vultr-${version}";