diff --git a/pkgs/development/python-modules/natsort/default.nix b/pkgs/development/python-modules/natsort/default.nix
index 805f5dc5de4..fc80f30aadc 100644
--- a/pkgs/development/python-modules/natsort/default.nix
+++ b/pkgs/development/python-modules/natsort/default.nix
@@ -29,6 +29,9 @@ buildPythonPackage rec {
     sha256 = "a633464dc3a22b305df0f27abcb3e83515898aa1fd0ed2f9726c3571a27258cf";
   };
 
+  # Does not support Python 2
+  disabled = !isPy3k;
+
   # testing based on project's tox.ini
   # natsort_keygen has pytest mock issues
   checkPhase = ''