diff --git a/pkgs/development/python-modules/pycryptodomex/default.nix b/pkgs/development/python-modules/pycryptodomex/default.nix
index d58821569e6..b350a3fb93b 100644
--- a/pkgs/development/python-modules/pycryptodomex/default.nix
+++ b/pkgs/development/python-modules/pycryptodomex/default.nix
@@ -2,7 +2,7 @@
 
 buildPythonPackage rec {
   pname = "pycryptodomex";
-  version = "3.9.9";
+  version = "3.10.1";
 
   meta = {
     description = "A self-contained cryptographic library for Python";
@@ -12,6 +12,6 @@ buildPythonPackage rec {
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "7b5b7c5896f8172ea0beb283f7f9428e0ab88ec248ce0a5b8c98d73e26267d51";
+    sha256 = "sha256-VBzT4+JS+xmntI9CC3mLU0gzArf+TZlUyUdgXQomPWI=";
   };
 }