diff --git a/pkgs/applications/networking/browsers/chromium/source/default.nix b/pkgs/applications/networking/browsers/chromium/source/default.nix
index 4e568aed594..a566c4bb1c8 100644
--- a/pkgs/applications/networking/browsers/chromium/source/default.nix
+++ b/pkgs/applications/networking/browsers/chromium/source/default.nix
@@ -41,10 +41,13 @@ in stdenv.mkDerivation {
     done
   '';
 
-  patches =
-    singleton ./nix_plugin_paths_46.patch ++
-    singleton ./build_fixes_46.patch ++
-    singleton ./widevine.patch;
+  patches = [
+    ./build_fixes_46.patch
+    ./widevine.patch
+    (if versionOlder version "50.0.0.0"
+     then ./nix_plugin_paths_46.patch
+     else ./nix_plugin_paths_50.patch)
+  ];
 
   patchPhase = let
     diffmod = sym: "/^${sym} /{s/^${sym} //;${transform ""};s/^/${sym} /}";
diff --git a/pkgs/applications/networking/browsers/chromium/source/nix_plugin_paths_50.patch b/pkgs/applications/networking/browsers/chromium/source/nix_plugin_paths_50.patch
new file mode 100644
index 00000000000..062098a8522
--- /dev/null
+++ b/pkgs/applications/networking/browsers/chromium/source/nix_plugin_paths_50.patch
@@ -0,0 +1,75 @@
+diff --git a/chrome/common/chrome_paths.cc b/chrome/common/chrome_paths.cc
+index 74bf041..5f34198 100644
+--- a/chrome/common/chrome_paths.cc
++++ b/chrome/common/chrome_paths.cc
+@@ -66,21 +66,14 @@ static base::LazyInstance<base::FilePath>
+     g_invalid_specified_user_data_dir = LAZY_INSTANCE_INITIALIZER;
+ 
+ // Gets the path for internal plugins.
+-bool GetInternalPluginsDirectory(base::FilePath* result) {
+-#if defined(OS_MACOSX)
+-  // If called from Chrome, get internal plugins from a subdirectory of the
+-  // framework.
+-  if (base::mac::AmIBundled()) {
+-    *result = chrome::GetFrameworkBundlePath();
+-    DCHECK(!result->empty());
+-    *result = result->Append("Internet Plug-Ins");
+-    return true;
+-  }
+-  // In tests, just look in the module directory (below).
+-#endif
+-
+-  // The rest of the world expects plugins in the module directory.
+-  return PathService::Get(base::DIR_MODULE, result);
++bool GetInternalPluginsDirectory(base::FilePath* result,
++                                 const std::string& ident) {
++  std::string full_env = std::string("NIX_CHROMIUM_PLUGIN_PATH_") + ident;
++  const char* value = getenv(full_env.c_str());
++  if (value == NULL)
++      return PathService::Get(base::DIR_MODULE, result);
++  else
++      *result = base::FilePath(value);
+ }
+ 
+ #if defined(OS_WIN)
+@@ -253,11 +246,11 @@ bool PathProvider(int key, base::FilePath* result) {
+       create_dir = true;
+       break;
+     case chrome::DIR_INTERNAL_PLUGINS:
+-      if (!GetInternalPluginsDirectory(&cur))
++      if (!GetInternalPluginsDirectory(&cur, "ALL"))
+         return false;
+       break;
+     case chrome::DIR_PEPPER_FLASH_PLUGIN:
+-      if (!GetInternalPluginsDirectory(&cur))
++      if (!GetInternalPluginsDirectory(&cur, "PEPPERFLASH"))
+         return false;
+       cur = cur.Append(kPepperFlashBaseDirectory);
+       break;
+@@ -314,7 +307,7 @@ bool PathProvider(int key, base::FilePath* result) {
+     // We currently need a path here to look up whether the plugin is disabled
+     // and what its permissions are.
+     case chrome::FILE_NACL_PLUGIN:
+-      if (!GetInternalPluginsDirectory(&cur))
++      if (!GetInternalPluginsDirectory(&cur, "NACL"))
+         return false;
+       cur = cur.Append(kInternalNaClPluginFileName);
+       break;
+@@ -349,7 +342,7 @@ bool PathProvider(int key, base::FilePath* result) {
+         cur = cur.DirName();
+       }
+ #else
+-      if (!GetInternalPluginsDirectory(&cur))
++      if (!GetInternalPluginsDirectory(&cur, "PNACL"))
+         return false;
+ #endif
+       cur = cur.Append(FILE_PATH_LITERAL("pnacl"));
+@@ -366,7 +359,7 @@ bool PathProvider(int key, base::FilePath* result) {
+     // In the component case, this is the source adapter. Otherwise, it is the
+     // actual Pepper module that gets loaded.
+     case chrome::FILE_WIDEVINE_CDM_ADAPTER:
+-      if (!GetInternalPluginsDirectory(&cur))
++      if (!GetInternalPluginsDirectory(&cur, "WIDEVINE"))
+         return false;
+       cur = cur.AppendASCII(kWidevineCdmAdapterFileName);
+       break;
diff --git a/pkgs/applications/networking/browsers/chromium/source/sources.nix b/pkgs/applications/networking/browsers/chromium/source/sources.nix
index ffb9ff11068..ffec5c8b807 100644
--- a/pkgs/applications/networking/browsers/chromium/source/sources.nix
+++ b/pkgs/applications/networking/browsers/chromium/source/sources.nix
@@ -1,19 +1,18 @@
 # This file is autogenerated from update.sh in the parent directory.
 {
   beta = {
-    sha256 = "07i4vqswkijnl7wi6r1a0n1jq54ackm01yf8h3hwcik8q10i1aq5";
-    sha256bin64 = "16pwimg672qaqb89zdvsr8dr7bz50mz7zf6cl0cf45kz7sn8wwlh";
-    version = "49.0.2623.63";
+    sha256 = "1xc2npbc829nxria1j37kxyy95jkalkkphxgv24if0ibn62lrzd4";
+    sha256bin64 = "1arm15g3vmm3zlvcql3qylw1fhrn5ddzl2v8mkpb3a251m425dsi";
+    version = "49.0.2623.75";
   };
   dev = {
-    sha256 = "1xc66zsjd5snydf60di2k2vzwwcqs1p16yn4jbpj2khm9cmxmkmf";
-    sha256bin64 = "06v7r76pbc979f7ahmln0hmxzd8ipirh4128i0ygidj71xmg51mm";
-    version = "50.0.2657.0";
+    sha256 = "04j0nyz20gi7vf1javbw06wrqpkfw6vg024i3wkgx42hzd6hjgw4";
+    sha256bin64 = "12ff4q615rwakgpr9v84p55maasqb4vg61s89vgxrlsgqrmkahg4";
+    version = "50.0.2661.11";
   };
   stable = {
-    sha256 = "03sdm09cnwq8a056rfljql7mz0s17fngfnm5q3p5xwakr2sbj7ka";
-    sha256bin32 = "157m88nafb8svpkv11rzpcfvak6486wx43rmbssg52x2k0vas0bl";
-    sha256bin64 = "036pcma8qczja803h9r1nlm0ypm4zblmy6q7pkwlgmn3r4r3n7i0";
-    version = "48.0.2564.116";
+    sha256 = "1xc2npbc829nxria1j37kxyy95jkalkkphxgv24if0ibn62lrzd4";
+    sha256bin64 = "01qi5jmlmdpy6icc4y51bn5a063mxrnkncg3pbmbl4r02vqca5jh";
+    version = "49.0.2623.75";
   };
 }