diff --git a/pkgs/development/python-modules/pybind11/default.nix b/pkgs/development/python-modules/pybind11/default.nix
index 37e55617023..94a25b2858e 100644
--- a/pkgs/development/python-modules/pybind11/default.nix
+++ b/pkgs/development/python-modules/pybind11/default.nix
@@ -12,27 +12,15 @@
 
 buildPythonPackage rec {
   pname = "pybind11";
-  version = "2.3.0";
+  version = "2.4.3";
 
   src = fetchFromGitHub {
     owner = "pybind";
     repo = pname;
     rev = "v${version}";
-    sha256 = "11b6dniri8m05spfd2a19irz82shf4sdca73566bniggrf3zclnf";
+    sha256 = "0k89w4bsfbpzw963ykg1cyszi3h3nk393qd31m6y46pcfxkqh4rd";
   };
 
-  patches = [
-    (fetchpatch {
-      url = https://github.com/pybind/pybind11/commit/44a40dd61e5178985cfb1150cf05e6bfcec73042.patch;
-      sha256 = "047nzyfsihswdva96hwchnp4gj2mlbiqvmkdnhxrfi9sji8x31ka";
-    })
-    (fetchpatch {
-      name = "pytest-4-excinfo-fix.patch";
-      url = https://github.com/pybind/pybind11/commit/9fd4712121fdbb6202a35be4c788525e6c8ab826.patch;
-      sha256 = "07jjv8jlbszvr2grpm5xqxjac7jb0y68lgb1jcbb93k9vyp1hr33";
-    })
-  ];
-
   dontUseCmakeConfigure = true;
 
   checkInputs = [ pytest cmake ]