diff --git a/.github/CODEOWNERS b/.github/CODEOWNERS
new file mode 100644
index 00000000000..268f2c032ad
--- /dev/null
+++ b/.github/CODEOWNERS
@@ -0,0 +1,20 @@
+# CODEOWNERS file
+#
+# This file is used to describe who owns what in this repository. This file does not
+# replace `meta.maintainers` but is instead used for other things than derivations
+# and modules, like documentation, package sets, and other assets.
+#
+# For documentation on this file, see https://help.github.com/articles/about-codeowners/
+# Mentioned users will get code review requests.
+
+# Python-related code and docs
+pkgs/top-level/python-packages.nix	@FRidh
+pkgs/development/interpreters/python/*	@FRidh
+pkgs/development/python-modules/*	@FRidh
+doc/languages-frameworks/python.md	@FRidh
+
+# Darwin-related
+pkgs/stdenv/darwin/*    @copumpkin @LnL7
+pkgs/os-specific/darwin/*   @LnL7
+pkgs/os-specific/darwin/apple-source-releases/* @copumpkin
+
diff --git a/.mention-bot b/.mention-bot
deleted file mode 100644
index 33c7e41c1dc..00000000000
--- a/.mention-bot
+++ /dev/null
@@ -1,14 +0,0 @@
-{
-  "userBlacklist": [
-    "civodul",
-    "jhasse",
-    "shlevy",
-    "bbenoist"
-  ],
-  "alwaysNotifyForPaths": [
-    { "name": "FRidh", "files": ["pkgs/top-level/python-packages.nix", "pkgs/development/interpreters/python/*", "pkgs/development/python-modules/*" ] },
-    { "name": "LnL7", "files": ["pkgs/stdenv/darwin/*", "pkgs/os-specific/darwin/*"] },
-    { "name": "copumpkin", "files": ["pkgs/stdenv/darwin/*", "pkgs/os-specific/darwin/apple-source-releases/*"] }
-  ],
-  "fileBlacklist": ["pkgs/top-level/all-packages.nix"]
-}