diff --git a/pkgs/development/libraries/libgda/default.nix b/pkgs/development/libraries/libgda/default.nix
index 27032607996..a1871f6b2e6 100644
--- a/pkgs/development/libraries/libgda/default.nix
+++ b/pkgs/development/libraries/libgda/default.nix
@@ -15,9 +15,18 @@ assert postgresSupport -> postgresql != null;
     url = "mirror://gnome/sources/${pname}/${stdenv.lib.versions.majorMinor version}/${pname}-${version}.tar.xz";
     sha256 = "16vxv2qvysh22s8h9h6irx96sacagxkz0i4qgi1wc6ibly6fvjjr";
   };
-  configureFlags = with stdenv.lib; [ "--enable-gi-system-install=no" ]
-    ++ (optional (mysqlSupport) "--with-mysql=yes")
-    ++ (optional (postgresSupport) "--with-postgres=yes");
+  configureFlags = with stdenv.lib; [
+    "--enable-gi-system-install=no"
+    "--with-mysql=${if mysqlSupport then "yes" else "no"}"
+    "--with-postgres=${if postgresSupport then "yes" else "no"}"
+
+    # macOS builds use the sqlite source code that comes with libgda,
+    # as opposed to using the system or brewed sqlite3, which is not supported on macOS,
+    # as mentioned in https://github.com/GNOME/libgda/blob/95eeca4b0470f347c645a27f714c62aa6e59f820/libgda/sqlite/README#L31,
+    # which references the paper https://web.archive.org/web/20100610151539/http://lattice.umiacs.umd.edu/files/functions_tr.pdf
+    # See also https://github.com/Homebrew/homebrew-core/blob/104f9ecd02854a82372b64d63d41356555378a52/Formula/libgda.rb
+    "--enable-system-sqlite=${if stdenv.isDarwin then "no" else "yes"}"
+  ];
 
   enableParallelBuilding = true;
 
@@ -39,6 +48,6 @@ assert postgresSupport -> postgresql != null;
     homepage = https://www.gnome-db.org/;
     license = [ licenses.lgpl2 licenses.gpl2 ];
     maintainers = gnome3.maintainers;
-    platforms = platforms.linux;
+    platforms = platforms.linux ++ platforms.darwin;
   };
 }