diff --git a/pkgs/development/misc/newlib/default.nix b/pkgs/development/misc/newlib/default.nix
index 193ec53d5ad..93c50ea3cc5 100644
--- a/pkgs/development/misc/newlib/default.nix
+++ b/pkgs/development/misc/newlib/default.nix
@@ -1,4 +1,9 @@
-{ stdenv, fetchurl, buildPackages }:
+{ stdenv, fetchurl, buildPackages
+, # "newlib-nano" is what the official ARM embedded toolchain calls this build
+  # configuration that prioritizes low space usage. We include it as a preset
+  # for embedded projects striving for a similar configuration.
+  nanoizeNewlib ? false
+}:
 
 let version = "3.3.0";
 in stdenv.mkDerivation {
@@ -22,10 +27,21 @@ in stdenv.mkDerivation {
 
     "--disable-newlib-supplied-syscalls"
     "--disable-nls"
+    "--enable-newlib-retargetable-locking"
+  ] ++ (if !nanoizeNewlib then [
     "--enable-newlib-io-long-long"
     "--enable-newlib-register-fini"
-    "--enable-newlib-retargetable-locking"
-  ];
+  ] else [
+    "--enable-newlib-reent-small"
+    "--disable-newlib-fvwrite-in-streamio"
+    "--disable-newlib-fseek-optimization"
+    "--disable-newlib-wide-orient"
+    "--enable-newlib-nano-malloc"
+    "--disable-newlib-unbuf-stream-opt"
+    "--enable-lite-exit"
+    "--enable-newlib-global-atexit"
+    "--enable-newlib-nano-formatted-io"
+  ]);
 
   dontDisableStatic = true;
 
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 94ceaf0f720..3470d482a8c 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -15006,6 +15006,7 @@ in
     else if name == "newlib" && stdenv.targetPlatform.isVc4 then targetPackages.vc4-newlib or vc4-newlib
     else if name == "newlib" && stdenv.targetPlatform.isOr1k then targetPackages.or1k-newlib or or1k-newlib
     else if name == "newlib" then targetPackages.newlibCross or newlibCross
+    else if name == "newlib-nano" then targetPackages.newlib-nanoCross or newlib-nanoCross
     else if name == "musl" then targetPackages.muslCross or muslCross
     else if name == "msvcrt" then targetPackages.windows.mingw_w64 or windows.mingw_w64
     else if name == "libSystem" then
@@ -31621,7 +31622,15 @@ in
   newlib = callPackage ../development/misc/newlib { };
   newlibCross = callPackage ../development/misc/newlib {
     stdenv = crossLibcStdenv;
-    };
+  };
+
+  newlib-nano = callPackage ../development/misc/newlib {
+    nanoizeNewlib = true;
+  };
+  newlib-nanoCross = callPackage ../development/misc/newlib {
+    nanoizeNewlib = true;
+    stdenv = crossLibcStdenv;
+  };
 
   omnisharp-roslyn = callPackage ../development/tools/omnisharp-roslyn { };