diff --git a/pkgs/applications/virtualization/virtualbox/guest-additions/default.nix b/pkgs/applications/virtualization/virtualbox/guest-additions/default.nix
index 08b6fa63e84..e20fbf73190 100644
--- a/pkgs/applications/virtualization/virtualbox/guest-additions/default.nix
+++ b/pkgs/applications/virtualization/virtualbox/guest-additions/default.nix
@@ -1,5 +1,5 @@
 { stdenv, fetchurl, lib, patchelf, cdrkit, kernel, which, makeWrapper
-, zlib, xorg, dbus, virtualbox }:
+, zlib, xorg, dbus, virtualbox, dos2unix }:
 
 let
   version = virtualbox.version;
@@ -32,9 +32,6 @@ in stdenv.mkDerivation {
   KERN_DIR = "${kernel.dev}/lib/modules/${kernel.modDirVersion}/build";
   KERN_INCL = "${kernel.dev}/lib/modules/${kernel.modDirVersion}/source/include";
 
-  # If you add a patch you probably need this.
-  #patchFlags = [ "-p1" "-d" "install/src/vboxguest-${version}" ];
-
   hardeningDisable = [ "pic" ];
 
   NIX_CFLAGS_COMPILE = "-Wno-error=incompatible-pointer-types -Wno-error=implicit-function-declaration";
@@ -42,11 +39,18 @@ in stdenv.mkDerivation {
   nativeBuildInputs = [ patchelf makeWrapper ];
   buildInputs = [ cdrkit ] ++ kernel.moduleBuildDependencies;
 
-  postPatch = ''
+
+  prePatch = ''
     substituteInPlace src/vboxguest-${version}/vboxvideo/vbox_ttm.c \
       --replace "<ttm/" "<drm/ttm/"
+    ${dos2unix}/bin/dos2unix src/vboxguest-${version}/vboxguest/r0drv/linux/mp-r0drv-linux.c
   '';
 
+  patchFlags = [ "-p1" "-d" "src/vboxguest-${version}" ];
+  # Kernel 5.3 fix, should be fixed with VirtualBox 6.0.14
+  # https://www.virtualbox.org/ticket/18911
+  patches = [ ./kernel-5.3-fix.patch ];
+
   unpackPhase = ''
     ${if stdenv.hostPlatform.system == "i686-linux" || stdenv.hostPlatform.system == "x86_64-linux" then ''
         isoinfo -J -i $src -x /VBoxLinuxAdditions.run > ./VBoxLinuxAdditions.run
diff --git a/pkgs/applications/virtualization/virtualbox/guest-additions/kernel-5.3-fix.patch b/pkgs/applications/virtualization/virtualbox/guest-additions/kernel-5.3-fix.patch
new file mode 100644
index 00000000000..0bdd9ec1056
--- /dev/null
+++ b/pkgs/applications/virtualization/virtualbox/guest-additions/kernel-5.3-fix.patch
@@ -0,0 +1,50 @@
+--- a/vboxguest/r0drv/linux/mp-r0drv-linux.c
++++ a/vboxguest/r0drv/linux/mp-r0drv-linux.c
+@@ -283,12 +283,15 @@
+     if (RTCpuSetCount(&OnlineSet) > 1)
+     {
+         /* Fire the function on all other CPUs without waiting for completion. */
+-# if LINUX_VERSION_CODE >= KERNEL_VERSION(2, 6, 27)
++# if LINUX_VERSION_CODE >= KERNEL_VERSION(5, 3, 0)
++        smp_call_function(rtmpLinuxAllWrapper, &Args, 0 /* wait */);
++# elif LINUX_VERSION_CODE >= KERNEL_VERSION(2, 6, 27)
+         int rc = smp_call_function(rtmpLinuxAllWrapper, &Args, 0 /* wait */);
++        Assert(!rc); NOREF(rc);
+ # else
+         int rc = smp_call_function(rtmpLinuxAllWrapper, &Args, 0 /* retry */, 0 /* wait */);
+-# endif
+         Assert(!rc); NOREF(rc);
++# endif
+     }
+ #endif
+
+@@ -326,7 +329,6 @@
+ {
+ #ifdef CONFIG_SMP
+     IPRT_LINUX_SAVE_EFL_AC();
+-    int rc;
+     RTMPARGS Args;
+
+     RTTHREADPREEMPTSTATE PreemptState = RTTHREADPREEMPTSTATE_INITIALIZER;
+@@ -337,14 +339,17 @@
+     Args.cHits = 0;
+
+     RTThreadPreemptDisable(&PreemptState);
+-# if LINUX_VERSION_CODE >= KERNEL_VERSION(2, 6, 27)
+-    rc = smp_call_function(rtmpLinuxWrapper, &Args, 1 /* wait */);
++# if LINUX_VERSION_CODE >= KERNEL_VERSION(5, 3, 0)
++    smp_call_function(rtmpLinuxWrapper, &Args, 1 /* wait */);
++# elif LINUX_VERSION_CODE >= KERNEL_VERSION(2, 6, 27)
++    int rc = smp_call_function(rtmpLinuxWrapper, &Args, 1 /* wait */);
++    Assert(rc == 0); NOREF(rc);
+ # else /* older kernels */
+-    rc = smp_call_function(rtmpLinuxWrapper, &Args, 0 /* retry */, 1 /* wait */);
++    int rc = smp_call_function(rtmpLinuxWrapper, &Args, 0 /* retry */, 1 /* wait */);
++    Assert(rc == 0); NOREF(rc);
+ # endif /* older kernels */
+     RTThreadPreemptRestore(&PreemptState);
+
+-    Assert(rc == 0); NOREF(rc);
+     IPRT_LINUX_RESTORE_EFL_AC();
+ #else
+     RT_NOREF(pfnWorker, pvUser1, pvUser2);