diff --git a/pkgs/development/libraries/science/math/amd-blis/default.nix b/pkgs/development/libraries/science/math/amd-blis/default.nix
new file mode 100644
index 00000000000..9bddba0261f
--- /dev/null
+++ b/pkgs/development/libraries/science/math/amd-blis/default.nix
@@ -0,0 +1,67 @@
+{ stdenv
+, fetchFromGitHub
+, perl
+, python3
+
+# Enable BLAS interface with 64-bit integer width.
+, blas64 ? false
+
+# Target architecture, use "zen" or "zen2", optimization for Zen and
+# other families is pretty much mutually exclusive in the AMD fork of
+# BLIS.
+, withArchitecture ? "zen"
+
+# Enable OpenMP-based threading.
+, withOpenMP ? true
+}:
+
+let
+  threadingSuffix = if withOpenMP then "-mt" else "";
+  blasIntSize = if blas64 then "64" else "32";
+in stdenv.mkDerivation rec {
+  pname = "amd-blis";
+  version = "2.2";
+
+  src = fetchFromGitHub {
+    owner = "amd";
+    repo = "blis";
+    rev = version;
+    sha256 = "1b2f5bwi0gkw2ih2rb7wfzn3m9hgg7k270kg43rmzpr2acpy86xa";
+  };
+
+  inherit blas64;
+
+  nativeBuildInputs = [
+    perl
+    python3
+  ];
+
+  doCheck = true;
+
+  enableParallelBuilding = true;
+
+  configureFlags = [
+    "--enable-cblas"
+    "--blas-int-size=${blasIntSize}"
+  ] ++ stdenv.lib.optionals withOpenMP [ "--enable-threading=openmp" ]
+    ++ [ withArchitecture ];
+
+  postPatch = ''
+    patchShebangs configure build/flatten-headers.py
+  '';
+
+  postInstall = ''
+    ln -s $out/lib/libblis${threadingSuffix}.so.2 $out/lib/libblas.so.3
+    ln -s $out/lib/libblis${threadingSuffix}.so.2 $out/lib/libcblas.so.3
+    ln -s $out/lib/libblas.so.3 $out/lib/libblas.so
+    ln -s $out/lib/libcblas.so.3 $out/lib/libcblas.so
+  '';
+
+  meta = with stdenv.lib; {
+    description = "BLAS-compatible library optimized for AMD CPUs";
+    homepage = "https://developer.amd.com/amd-aocl/blas-library/";
+    license = licenses.bsd3;
+    maintainers = [ maintainers.danieldk ];
+    platforms = [ "x86_64-linux" ];
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index e105c061aa5..42c87c667d7 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -25305,6 +25305,8 @@ in
 
   almonds = callPackage ../applications/science/math/almonds { };
 
+  amd-blis = callPackage ../development/libraries/science/math/amd-blis { };
+
   arpack = callPackage ../development/libraries/science/math/arpack { };
 
   blas = callPackage ../build-support/alternatives/blas { };