diff --git a/pkgs/servers/matrix-synapse/default.nix b/pkgs/servers/matrix-synapse/default.nix
index db19f6a1337..4bbc54b02de 100644
--- a/pkgs/servers/matrix-synapse/default.nix
+++ b/pkgs/servers/matrix-synapse/default.nix
@@ -24,11 +24,11 @@ let
 in
 with py.pkgs; buildPythonApplication rec {
   pname = "matrix-synapse";
-  version = "1.44.0";
+  version = "1.45.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-oH8FXHSa120/Fys21UJfAAFPehJxEbQ8Op98PYkK8dE=";
+    sha256 = "sha256-8ZcZdQbNxrRy91gxKSoasu8QmdV27T7HeWIRz0bStzY=";
   };
 
   patches = [