diff --git a/pkgs/development/libraries/glib-networking/default.nix b/pkgs/development/libraries/glib-networking/default.nix
index 9336e5bbae9..954e5d1f6b5 100644
--- a/pkgs/development/libraries/glib-networking/default.nix
+++ b/pkgs/development/libraries/glib-networking/default.nix
@@ -15,7 +15,8 @@ stdenv.mkDerivation rec {
 
   outputs = [ "out" "dev" ]; # to deal with propagatedBuildInputs
 
-  configureFlags = "--with-ca-certificates=/etc/ssl/certs/ca-certificates.crt";
+  configureFlags = if stdenv.isDarwin then "--without-ca-certificates"
+    else "--with-ca-certificates=/etc/ssl/certs/ca-certificates.crt";
 
   LDFLAGS = stdenv.lib.optionalString stdenv.isDarwin "-lintl";