diff --git a/pkgs/development/python-modules/pyscard/default.nix b/pkgs/development/python-modules/pyscard/default.nix
index 4bda0b3c65c..d563a62a46b 100644
--- a/pkgs/development/python-modules/pyscard/default.nix
+++ b/pkgs/development/python-modules/pyscard/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchPypi, buildPythonPackage, swig, pcsclite, PCSC }:
+{ stdenv, fetchPypi, fetchpatch, buildPythonPackage, swig, pcsclite, PCSC }:
 
 let
   # Package does not support configuring the pcsc library.
@@ -30,6 +30,21 @@ buildPythonPackage rec {
   NIX_CFLAGS_COMPILE = optionalString (! withApplePCSC)
     "-I ${getDev pcsclite}/include/PCSC";
 
+  # The error message differs depending on the macOS host version.
+  # Since Nix reports a constant host version, but proxies to the
+  # underlying library, it's not possible to determine the correct
+  # expected error message.  This patch allows both errors to be
+  # accepted.
+  # See: https://github.com/LudovicRousseau/pyscard/issues/77
+  # Building with python from nix on macOS version 10.13 or
+  # greater still causes this issue to occur.
+  patches = optionals withApplePCSC [
+    (fetchpatch {
+      url = "https://github.com/LudovicRousseau/pyscard/commit/945e9c4cd4036155691f6ce9706a84283206f2ef.patch";
+      sha256 = "19n8w1wzn85zywr6xf04d8nfg7sgzjyvxp1ccp3rgfr4mcc36plc";
+    })
+  ];
+
   propagatedBuildInputs = if withApplePCSC then [ PCSC ] else [ pcsclite ];
   nativeBuildInputs = [ swig ];
 
diff --git a/pkgs/development/python-modules/pyscard/ignore-macos-bug.patch b/pkgs/development/python-modules/pyscard/ignore-macos-bug.patch
deleted file mode 100644
index 62b20477c9f..00000000000
--- a/pkgs/development/python-modules/pyscard/ignore-macos-bug.patch
+++ /dev/null
@@ -1,22 +0,0 @@
-diff --git a/test/test_SCardGetErrorMessage.py b/test/test_SCardGetErrorMessage.py
-old mode 100644
-new mode 100755
-index c6fe755..c1217f5
---- a/test/test_SCardGetErrorMessage.py
-+++ b/test/test_SCardGetErrorMessage.py
-@@ -29,12 +29,10 @@ class TestError(unittest.TestCase):
-         self.assertEqual(res, expected)
- 
-         res = SCardGetErrorMessage(1)
-+        expected = "Unknown error: 0x00000001"
-         # macOS bug not yet fixed
--        if get_platform().startswith('macosx-') and get_platform() < 'macosx-10.13':
--            expected = "Unkown error: 0x00000001"
--        else:
--            expected = "Unknown error: 0x00000001"
--        self.assertEqual(res, expected)
-+        macos_bug_expected = "Unkown error: 0x00000001"
-+        self.assertIn(res, [expected, macos_bug_expected])
- 
- 
- if __name__ == '__main__':