diff --git a/pkgs/tools/misc/yubico-piv-tool/default.nix b/pkgs/tools/misc/yubico-piv-tool/default.nix
index f081f94a147..39150cfed7e 100644
--- a/pkgs/tools/misc/yubico-piv-tool/default.nix
+++ b/pkgs/tools/misc/yubico-piv-tool/default.nix
@@ -1,4 +1,6 @@
-{ stdenv, fetchurl, pkgconfig, openssl, pcsclite, check }:
+{ stdenv, fetchurl, pkgconfig, openssl, check, pcsclite, PCSC
+, withApplePCSC ? stdenv.isDarwin
+}:
 
 stdenv.mkDerivation rec {
   name = "yubico-piv-tool-2.0.0";
@@ -9,9 +11,10 @@ stdenv.mkDerivation rec {
   };
 
   nativeBuildInputs = [ pkgconfig ];
-  buildInputs = [ openssl pcsclite check ];
+  buildInputs = [ openssl check ]
+    ++ (if withApplePCSC then [ PCSC ] else [ pcsclite ]);
 
-  configureFlags = [ "--with-backend=pcsc" ];
+  configureFlags = [ "--with-backend=${if withApplePCSC then "macscard" else "pcsc"}" ];
 
   meta = with stdenv.lib; {
     homepage = https://developers.yubico.com/yubico-piv-tool/;
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index a5fb447f8a0..cd5cfa7d7b4 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -14902,7 +14902,9 @@ in
 
   yubico-pam = callPackage ../development/libraries/yubico-pam { };
 
-  yubico-piv-tool = callPackage ../tools/misc/yubico-piv-tool { };
+  yubico-piv-tool = callPackage ../tools/misc/yubico-piv-tool {
+    inherit (darwin.apple_sdk.frameworks) PCSC;
+  };
 
   yubikey-manager = callPackage ../tools/misc/yubikey-manager { };