diff --git a/pkgs/development/interpreters/php/default.nix b/pkgs/development/interpreters/php/default.nix
index c967ed2b862..0ef1c492d58 100644
--- a/pkgs/development/interpreters/php/default.nix
+++ b/pkgs/development/interpreters/php/default.nix
@@ -11,6 +11,8 @@ let
 
     let php7 = lib.versionAtLeast version "7.0";
         mysqlHeaders = mysql.lib.dev or mysql;
+        mysqlndSupport = config.php.mysqlnd or false;
+        mysqlBuildInputs = if mysqlndSupport then [] else [ mysqlHeaders ];
 
     in composableDerivation.composableDerivation {} (fixed: {
 
@@ -110,13 +112,13 @@ let
         };
 
         mysql = {
-          configureFlags = ["--with-mysql"];
-          buildInputs = [ mysqlHeaders ];
+          configureFlags = ["--with-mysql${if mysqlndSupport then "=mysqlnd" else ""}"];
+          buildInputs = mysqlBuildInputs;
         };
 
         mysqli = {
-          configureFlags = ["--with-mysqli=${mysqlHeaders}/bin/mysql_config"];
-          buildInputs = [ mysqlHeaders ];
+          configureFlags = ["--with-mysqli=${if mysqlndSupport then "mysqlnd" else "${mysqlHeaders}/bin/mysql_config"}"];
+          buildInputs = mysqlBuildInputs;
         };
 
         mysqli_embedded = {
@@ -126,8 +128,8 @@ let
         };
 
         pdo_mysql = {
-          configureFlags = ["--with-pdo-mysql=${mysqlHeaders}"];
-          buildInputs = [ mysqlHeaders ];
+          configureFlags = ["--with-pdo-mysql=${if mysqlndSupport then "mysqlnd" else mysqlHeaders}"];
+          buildInputs = mysqlBuildInputs;
         };
 
         bcmath = {