diff --git a/pkgs/development/libraries/ffmpeg-full/default.nix b/pkgs/development/libraries/ffmpeg-full/default.nix
index 95be159b2e1..666aafef7f4 100644
--- a/pkgs/development/libraries/ffmpeg-full/default.nix
+++ b/pkgs/development/libraries/ffmpeg-full/default.nix
@@ -242,8 +242,6 @@ stdenv.mkDerivation rec {
   pname = "ffmpeg-full";
   inherit (ffmpeg) src version;
 
-  patches = [ ./prefer-libdav1d-over-libaom.patch ];
-
   prePatch = ''
     patchShebangs .
   '' + stdenv.lib.optionalString stdenv.isDarwin ''
diff --git a/pkgs/development/libraries/ffmpeg-full/prefer-libdav1d-over-libaom.patch b/pkgs/development/libraries/ffmpeg-full/prefer-libdav1d-over-libaom.patch
deleted file mode 100644
index 789bfc2674f..00000000000
--- a/pkgs/development/libraries/ffmpeg-full/prefer-libdav1d-over-libaom.patch
+++ /dev/null
@@ -1,19 +0,0 @@
-diff --git a/libavcodec/allcodecs.c b/libavcodec/allcodecs.c
-index d2f9a39ce5..2342399a8e 100644
---- a/libavcodec/allcodecs.c
-+++ b/libavcodec/allcodecs.c
-@@ -679,13 +679,13 @@ extern AVCodec ff_pcm_mulaw_at_encoder;
- extern AVCodec ff_pcm_mulaw_at_decoder;
- extern AVCodec ff_qdmc_at_decoder;
- extern AVCodec ff_qdm2_at_decoder;
-+extern AVCodec ff_libdav1d_decoder;
- extern AVCodec ff_libaom_av1_decoder;
- extern AVCodec ff_libaom_av1_encoder;
- extern AVCodec ff_libaribb24_decoder;
- extern AVCodec ff_libcelt_decoder;
- extern AVCodec ff_libcodec2_encoder;
- extern AVCodec ff_libcodec2_decoder;
--extern AVCodec ff_libdav1d_decoder;
- extern AVCodec ff_libdavs2_decoder;
- extern AVCodec ff_libfdk_aac_encoder;
- extern AVCodec ff_libfdk_aac_decoder;
diff --git a/pkgs/development/libraries/ffmpeg/4.nix b/pkgs/development/libraries/ffmpeg/4.nix
index 1a7c619a122..de1bfff6f91 100644
--- a/pkgs/development/libraries/ffmpeg/4.nix
+++ b/pkgs/development/libraries/ffmpeg/4.nix
@@ -5,8 +5,8 @@
 }@args:
 
 callPackage ./generic.nix (rec {
-  version = "4.2.3";
-  branch = "4.2";
-  sha256 = "0pkrariwjv25k7inwshch7b5820ly3hsp991amyb60rkqc8v4zi1";
+  version = "4.3";
+  branch = "4.3";
+  sha256 = "1qnnhd2b0g5sg72pclxs3i8sxzz0raky69k7w9cmpba9zh973s57";
   darwinFrameworks = [ Cocoa CoreMedia VideoToolbox ];
 } // args)
diff --git a/pkgs/development/libraries/nv-codec-headers/default.nix b/pkgs/development/libraries/nv-codec-headers/default.nix
index f74030a02df..8d3c2179bff 100644
--- a/pkgs/development/libraries/nv-codec-headers/default.nix
+++ b/pkgs/development/libraries/nv-codec-headers/default.nix
@@ -2,12 +2,12 @@
 
 stdenv.mkDerivation rec {
   pname = "nv-codec-headers";
-  version = "9.0.18.1";
+  version = "9.1.23.1";
 
   src = fetchgit {
     url = "https://git.videolan.org/git/ffmpeg/nv-codec-headers.git";
     rev = "n${version}";
-    sha256 = "0354fivb92ix341jds7a7qn3mgwimrnxbganhlhr4vayj25c3hw5";
+    sha256 = "1xfvb3mhz6wfx9c732888xa82ivaig903lhvvrqqzs31qfznsplh";
   };
 
   makeFlags = [ "PREFIX=$(out)" ];