diff --git a/pkgs/applications/audio/chuck/clang.patch b/pkgs/applications/audio/chuck/clang.patch
new file mode 100644
index 00000000000..77227ef0fd4
--- /dev/null
+++ b/pkgs/applications/audio/chuck/clang.patch
@@ -0,0 +1,58 @@
+diff --git a/src/ugen_osc.cpp b/src/ugen_osc.cpp
+index 6b93c6b..dbefe4f 100644
+--- a/src/ugen_osc.cpp
++++ b/src/ugen_osc.cpp
+@@ -1232,7 +1232,7 @@ CK_DLL_CTRL( gen5_coeffs )
+     Chuck_Array8 * in_args = (Chuck_Array8 *)GET_CK_OBJECT(ARGS);
+     
+     // fprintf(stdout, "calling gen10coeffs, %d\n", weights);
+-    if(in_args<0) return;
++    if(in_args!=0) return;
+     size = in_args->size();
+     if(size >= genX_MAX_COEFFS) size = genX_MAX_COEFFS - 1;
+     
+@@ -1287,7 +1287,7 @@ CK_DLL_CTRL( gen7_coeffs )
+     Chuck_Array8 * in_args = (Chuck_Array8 *)GET_CK_OBJECT(ARGS);
+     
+     // fprintf(stdout, "calling gen10coeffs, %d\n", weights);
+-    if(in_args<0) return;
++    if(in_args!=0) return;
+     size = in_args->size();
+     if(size >= genX_MAX_COEFFS) size = genX_MAX_COEFFS - 1;
+     
+@@ -1340,7 +1340,7 @@ CK_DLL_CTRL( gen9_coeffs )
+     Chuck_Array8 * weights = (Chuck_Array8 *)GET_CK_OBJECT(ARGS);
+     
+     // fprintf(stdout, "calling gen10coeffs, %d\n", weights);
+-    if(weights<0) return;
++    if(weights!=0) return;
+     size = weights->size();
+     if(size >= genX_MAX_COEFFS) size = genX_MAX_COEFFS - 1;
+     
+@@ -1390,7 +1390,7 @@ CK_DLL_CTRL( gen10_coeffs )
+     Chuck_Array8 * weights = (Chuck_Array8 *)GET_CK_OBJECT(ARGS);
+     
+     // fprintf(stdout, "calling gen10coeffs, %d\n", weights);
+-    if(weights<0) return;
++    if(weights!=0) return;
+     size = weights->size();
+     if(size >= genX_MAX_COEFFS) size = genX_MAX_COEFFS - 1;
+     
+@@ -1441,7 +1441,7 @@ CK_DLL_CTRL( gen17_coeffs )
+     Chuck_Array8 * weights = (Chuck_Array8 *)GET_CK_OBJECT(ARGS);
+     
+     // fprintf(stdout, "calling gen17coeffs, %d\n", weights);
+-    if(weights<0) return;
++    if(weights!=0) return;
+     size = weights->size();
+     if(size >= genX_MAX_COEFFS) size = genX_MAX_COEFFS - 1;
+     
+@@ -1502,7 +1502,7 @@ CK_DLL_CTRL( curve_coeffs )
+     Chuck_Array8 * weights = (Chuck_Array8 *)GET_CK_OBJECT(ARGS);
+     
+     // fprintf(stdout, "calling gen17coeffs, %d\n", weights);
+-    if(weights<0) goto done;
++    if(weights!=0) goto done;
+ 
+     nargs = weights->size();
+     if (nargs < 5 || (nargs % 3) != 2)  {   // check number of args
diff --git a/pkgs/applications/audio/chuck/default.nix b/pkgs/applications/audio/chuck/default.nix
index fd7f0c2b07c..e94172b0f87 100644
--- a/pkgs/applications/audio/chuck/default.nix
+++ b/pkgs/applications/audio/chuck/default.nix
@@ -1,4 +1,6 @@
-{ stdenv, fetchurl, alsaLib, bison, flex, libsndfile, which }:
+{ stdenv, fetchurl, alsaLib, bison, flex, libsndfile, which
+, AppKit, Carbon, CoreAudio, CoreMIDI, CoreServices, Kernel
+}:
 
 stdenv.mkDerivation rec {
   version = "1.3.5.2";
@@ -10,19 +12,24 @@ stdenv.mkDerivation rec {
   };
 
   buildInputs = [ bison flex libsndfile which ]
-    ++ stdenv.lib.optional (!stdenv.isDarwin) alsaLib;
+    ++ stdenv.lib.optional (!stdenv.isDarwin) alsaLib
+    ++ stdenv.lib.optional stdenv.isDarwin [ AppKit Carbon CoreAudio CoreMIDI CoreServices Kernel ];
 
-  patches = [ ./darwin-limits.patch ];
+  patches = [ ./clang.patch ./darwin-limits.patch ];
+
+  NIX_CFLAGS_COMPILE = stdenv.lib.optionalString stdenv.isDarwin "-Wno-missing-sysroot";
+  NIX_LDFLAGS = stdenv.lib.optionalString stdenv.isDarwin "-framework MultitouchSupport";
 
   postPatch = ''
     substituteInPlace src/makefile --replace "/usr/bin" "$out/bin"
     substituteInPlace src/makefile.osx --replace "xcodebuild" "/usr/bin/xcodebuild"
     substituteInPlace src/makefile.osx --replace "weak_framework" "framework"
+    substituteInPlace src/makefile.osx --replace "MACOSX_DEPLOYMENT_TARGET=10.5" "MACOSX_DEPLOYMENT_TARGET=$MACOSX_DEPLOYMENT_TARGET"
   '';
 
-  buildPhase =
-    stdenv.lib.optionals stdenv.isLinux  ["make -C src linux-alsa"] ++
-    stdenv.lib.optionals stdenv.isDarwin ["make -C src osx"];
+  buildPhase = ''
+    make -C src ${if stdenv.isDarwin then "osx" else "linux-alsa"}
+  '';
 
   installPhase = ''
     install -Dm755 ./src/chuck $out/bin/chuck
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index e8e6b900829..3fc37f091f1 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -14868,7 +14868,9 @@ with pkgs;
 
   chromiumDev = lowPrio (chromium.override { channel = "dev"; });
 
-  chuck = callPackage ../applications/audio/chuck { };
+  chuck = callPackage ../applications/audio/chuck {
+    inherit (darwin.apple_sdk.frameworks) AppKit Carbon CoreAudio CoreMIDI CoreServices Kernel;
+  };
 
   cinelerra = callPackage ../applications/video/cinelerra { };