diff --git a/doc/languages-frameworks/python.section.md b/doc/languages-frameworks/python.section.md
index 46491a785a7..e569cdaa935 100644
--- a/doc/languages-frameworks/python.section.md
+++ b/doc/languages-frameworks/python.section.md
@@ -1188,7 +1188,8 @@ community to help save time. No tool is preferred at the moment.
   expressions for your Python project. Note that [sharing derivations from
   pypi2nix with nixpkgs is possible but not
   encouraged](https://github.com/nix-community/pypi2nix/issues/222#issuecomment-443497376).
-- [python2nix](https://github.com/proger/python2nix) by Vladimir Kirillov.
+- [nixpkgs-pytools](https://github.com/nix-community/nixpkgs-pytools)
+- [poetry2nix](https://github.com/nix-community/poetry2nix)
 
 ### Deterministic builds
 
diff --git a/pkgs/tools/package-management/python2nix/default.nix b/pkgs/tools/package-management/python2nix/default.nix
deleted file mode 100644
index c36a488647a..00000000000
--- a/pkgs/tools/package-management/python2nix/default.nix
+++ /dev/null
@@ -1,19 +0,0 @@
-{ lib, fetchFromGitHub, pythonPackages }:
-
-pythonPackages.buildPythonApplication {
-  name = "python2nix-20140927";
-
-  src = fetchFromGitHub {
-    owner = "proger";
-    repo = "python2nix";
-    rev = "84e3a5bbe82e5d9d694d6db8dabf73def4ac917b";
-    sha256 = "022gr0gw6azfi3iq4ggb3fhkw2jljs6n5rncn45hb5liwakigj8i";
-  };
-
-  propagatedBuildInputs = with pythonPackages; [ requests pip setuptools ];
-
-  meta = with lib; {
-    maintainers = [ ];
-    platforms = platforms.all;
-  };
-}
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 39d4d388201..2a94e28cfc6 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -554,6 +554,7 @@ mapAliases ({
   phonon-backend-vlc = throw "phonon-backend-vlc: Please use libsForQt5.phonon-backend-vlc, as Qt4 support in this package has been removed."; # added 2019-11-22
   phonon = throw "phonon: Please use libsForQt5.phonon, as Qt4 support in this package has been removed."; # added 2019-11-22
   pynagsystemd = throw "pynagsystemd was removed as it was unmaintained and incompatible with recent systemd versions. Instead use its fork check_systemd."; # added 2020-10-24
+  python2nix = throw "python2nix has been removed as it is outdated. Use e.g. nixpkgs-pytools instead."; # added 2021-03-08
   qca-qt5 = libsForQt5.qca-qt5;  # added 2015-12-19
   qcsxcad = libsForQt5.qcsxcad;  # added 2020-11-05
   qr-filetransfer = throw ''"qr-filetransfer" has been renamed to "qrcp"''; # added 2020-12-02
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 904fa6e7c77..8ccf6eefa0f 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -11578,8 +11578,6 @@ in
   # Should eventually be moved inside Python interpreters.
   python-setup-hook = callPackage ../development/interpreters/python/setup-hook.nix { };
 
-  python2nix = callPackage ../tools/package-management/python2nix { };
-
   pythonDocs = recurseIntoAttrs (callPackage ../development/interpreters/python/cpython/docs {});
 
   pypi2nix = callPackage ../development/tools/pypi2nix {};