diff --git a/pkgs/development/libraries/jemalloc/default.nix b/pkgs/development/libraries/jemalloc/default.nix
index 8c8c181409d..ebe9ce46f9a 100644
--- a/pkgs/development/libraries/jemalloc/default.nix
+++ b/pkgs/development/libraries/jemalloc/default.nix
@@ -1,4 +1,8 @@
-{ stdenv, fetchurl }:
+{ stdenv, fetchurl,
+  # jemalloc is unable to correctly detect transparent hugepage support on
+  # ARM (https://github.com/jemalloc/jemalloc/issues/526), and the default
+  # kernel ARMv6/7 kernel does not enable it, so we explicitly disable support
+  thpSupport ? !stdenv.isArm }:
 
 stdenv.mkDerivation rec {
   name = "jemalloc-${version}";
@@ -12,7 +16,8 @@ stdenv.mkDerivation rec {
   # By default, jemalloc puts a je_ prefix onto all its symbols on OSX, which
   # then stops downstream builds (mariadb in particular) from detecting it. This
   # option should remove the prefix and give us a working jemalloc.
-  configureFlags = stdenv.lib.optional stdenv.isDarwin "--with-jemalloc-prefix=";
+  configureFlags = stdenv.lib.optional stdenv.isDarwin "--with-jemalloc-prefix="
+                   ++ stdenv.lib.optional (!thpSupport) "--disable-thp";
 
   doCheck = true;