diff --git a/pkgs/development/python-modules/diofant/default.nix b/pkgs/development/python-modules/diofant/default.nix
new file mode 100644
index 00000000000..c473f2fb420
--- /dev/null
+++ b/pkgs/development/python-modules/diofant/default.nix
@@ -0,0 +1,44 @@
+{ lib
+, isPy3k
+, buildPythonPackage
+, fetchPypi
+, pytestrunner
+, setuptools_scm
+, isort
+, mpmath
+, strategies
+}:
+
+buildPythonPackage rec {
+  pname = "diofant";
+  version = "0.10.0";
+
+  src = fetchPypi {
+    inherit version;
+    pname = "Diofant";
+    sha256 = "0qjg0mmz2cqxryr610mppx3virf1gslzrsk24304502588z53v8w";
+  };
+
+  nativeBuildInputs = [
+    isort
+    pytestrunner
+    setuptools_scm
+  ];
+
+  propagatedBuildInputs = [
+    mpmath
+    strategies
+  ];
+
+  # tests take ~1h
+  doCheck = false;
+
+  disabled = !isPy3k;
+
+  meta = with lib; {
+    description = "A Python CAS library";
+    homepage = "https://diofant.readthedocs.io/";
+    license = licenses.bsd3;
+    maintainers = with maintainers; [ suhr ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 5e3ea348bed..f3e774b91e3 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -502,6 +502,8 @@ in {
 
   diff_cover = callPackage ../development/python-modules/diff_cover { };
 
+  diofant = callPackage ../development/python-modules/diofant { };
+
   docrep = callPackage ../development/python-modules/docrep { };
 
   dominate = callPackage ../development/python-modules/dominate { };