diff --git a/pkgs/build-support/cc-wrapper/default.nix b/pkgs/build-support/cc-wrapper/default.nix
index a4370ff6793..7ae1c87e993 100644
--- a/pkgs/build-support/cc-wrapper/default.nix
+++ b/pkgs/build-support/cc-wrapper/default.nix
@@ -366,7 +366,9 @@ stdenv.mkDerivation {
     # There are a few tools (to name one libstdcxx5) which do not work
     # well with multi line flags, so make the flags single line again
     + ''
-      substituteInPlace $out/nix-support/libc-cflags --replace $'\n' ' '
+      if [ -e "$out/nix-support/libc-cflags" ]; then
+        substituteInPlace "$out/nix-support/libc-cflags" --replace $'\n' ' '
+      fi
 
       substituteAll ${./add-flags.sh} $out/nix-support/add-flags.sh
       substituteAll ${./add-hardening.sh} $out/nix-support/add-hardening.sh