diff --git a/pkgs/development/python-modules/guestfs/default.nix b/pkgs/development/python-modules/guestfs/default.nix
new file mode 100644
index 00000000000..238a1e9980b
--- /dev/null
+++ b/pkgs/development/python-modules/guestfs/default.nix
@@ -0,0 +1,20 @@
+{ stdenv, buildPythonPackage, fetchurl, libguestfs, qemu }:
+
+buildPythonPackage rec {
+  pname = "guestfs";
+  version = "1.40.1";
+
+  src = fetchurl {
+    url = "http://download.libguestfs.org/python/guestfs-${version}.tar.gz";
+    sha256 = "06a4b5xf1rkhnzfvck91n0z9mlkrgy90s9na5a8da2g4p776lhkf";
+  };
+
+  propagatedBuildInputs = [ libguestfs qemu ];
+
+  meta = with stdenv.lib; {
+    homepage = "http://libguestfs.org/guestfs-python.3.html";
+    description = "Use libguestfs from Python";
+    license = licenses.lgpl2Plus;
+    maintainers = with maintainers; [ grahamc ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 63d3e962b23..53148839594 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -406,6 +406,8 @@ in {
 
   gssapi = callPackage ../development/python-modules/gssapi { };
 
+  guestfs = callPackage ../development/python-modules/guestfs { };
+
   h5py = callPackage ../development/python-modules/h5py {
     hdf5 = pkgs.hdf5;
   };