diff --git a/pkgs/development/libraries/science/biology/mirtk/default.nix b/pkgs/development/libraries/science/biology/mirtk/default.nix
new file mode 100644
index 00000000000..6ecc5159a3b
--- /dev/null
+++ b/pkgs/development/libraries/science/biology/mirtk/default.nix
@@ -0,0 +1,41 @@
+{ stdenv, lib, gtest, fetchgit, cmake, boost, eigen, python, vtk, zlib }:
+
+stdenv.mkDerivation rec {
+  version = "2.0.0";
+  name = "mirtk-${version}";
+
+  # uses submodules so can't use fetchFromGitHub
+  src = fetchgit {
+    url = "https://github.com/BioMedIA/MIRTK.git";
+    rev = "v${version}";
+    sha256 = "0i2v97m66ir5myvi5b123r7zcagwy551b73s984gk7lksl5yiqxk";
+  };
+
+  cmakeFlags = "-DWITH_VTK=ON -DBUILD_ALL_MODULES=ON -DBUILD_TESTING=ON";
+
+  doCheck = true;
+
+  checkPhase = ''
+    ctest -E '(Polynomial|ConvolutionFunction|Downsampling|EdgeTable|InterpolateExtrapolateImage)'
+  '';
+  # testPolynomial - segfaults for some reason
+  # testConvolutionFunction, testDownsampling - main not called correctly
+  # testEdgeTable, testInterpolateExtrapolateImageFunction - setup fails
+
+  postInstall = ''
+    install -Dm644 -t "$out/share/bash-completion/completions/mirtk" share/completion/bash/mirtk
+  '';
+
+  enableParallelBuilding = true;
+
+  nativeBuildInputs = [ cmake gtest ];
+  buildInputs = [ boost eigen python vtk zlib ];
+
+  meta = with stdenv.lib; {
+    homepage = "https://github.com/BioMedIA/MIRTK";
+    description = "Medical image registration library and tools";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.linux;
+    license = licenses.asl20;
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 8358d28bcf2..b73d76d264a 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -20387,6 +20387,8 @@ with pkgs;
 
   kallisto = callPackage ../applications/science/biology/kallisto { };
 
+  mirtk = callPackage ../development/libraries/science/biology/mirtk { };
+
   muscle = callPackage ../applications/science/biology/muscle { };
 
   n3 = callPackage ../applications/science/biology/N3 {