716 lines
31 KiB
Plaintext
716 lines
31 KiB
Plaintext
DMT is Dimethyl Tryptamine = N,N Dimethyl 3-amino-ethyl indole.
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It is a powerful hallucinogen, the prototype of this class, and
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chemically related to psiloc(yb)in and more distantly to LSD.
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Dose: around 60 mg.
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Method of ingestion: usually smoked (inactive orally at reasonable doses.)
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Can be combined with monoamine oxidase inhibitors (MAOI) to make it
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orally active and increase the duration.
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Could be snuffed or or injected.
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Duration of action: 2-5 minutes of peak, around half an hour of cruise.
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Side effects: Stimulation and tactile hallucination during trip. No
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perceivable after-effects. No known long term side effects. May be
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some link with schizophrenia, since it has been detected in vivo.
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Status: illegal in USA, Australia, most places.
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History: is a component of some snuffs used by South American natives.
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also used in combination with MAOIs (harmaline etc.).
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Availability: Very rarely available from dealers; rarely synthesised.
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Available from a range of natural sources.
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Psychological effects: A very intense but brief trip, not really
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euphoric. Can be frightening because of the sudden onset.
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Not really a party drug, rather an interesting experience.
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More intense than LSD, but hallucinations and perceptual
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changes are of a somewhat different nature.
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(these are only my opinions and recollections)
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Jeremy
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=============================================================================
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There are three issues here which are a little confused:
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1) strength in the sense of effective dose,
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2) strength in terms of subjective intensity,
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3) being a superior hallucinogen in some subjective sense.
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Comparing DMT and LSD, the first is easy.
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The effective dose of LSD is around 100 ug, of DMT is around 60 mg,
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so in this sense, LSD is a much stronger hallucinogen.
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In terms of intensity, they are difficult to compare. Part of the intensity
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of DMT stems from the fact that the onset is virtually instantaneous;
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one is taken from feeling normal to the peak of the trip in the space
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of a few seconds, and this can be totally disorienting and frightening.
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DMT does not have the euphoria of LSD, in fact it can be quite
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uncomfortable. Also, the smoking of DMT is quite unpleasant compared
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with eating some small object. The types of hallucinations experienced
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within the peak of the DMT trip differ markedly from those in the peak
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of the LSD trip. This difference is very hard to describe, although
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one might contrast the dripping flowing colourful experience of LSD
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with the DMT visuals in which everything becomes super sharp to the
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point of being ripped into fragments, like placing a photo in a blender.
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There is some colour enhancement, but it is more like lightning-bolts
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of colour rather than flowing ripples of colour, and colours may
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be actually entirely changed and several multiple images seen at once.
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The 20-30 minute come-down of DMT is similar in experience and intensity
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to a small dose of LSD, however one is likely to be too shattered by
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the initial peak to worry about this much. The account Bob posted is
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highly subjective and metaphorical (as is this one, I suppose) and I
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doubt that many people would experience DMT in the way described there.
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However, extending the duration of DMT by the use of monoamineoxidase
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inhibitors (Ayahuasca,Yage,etc.) is supposed to be a very intense
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experience and could give one time to become more involved in it.
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It is possible to lose all contact with the senses and the world
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briefly while on DMT, as it is, e.g. from a combination of nitrous
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oxide and LSD. Also, psiloc(yb)in seems to have some similarity to
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DMT whilst retaining similarity to LSD, in that during the psilocin
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experience one can be transported into a different reality, although
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one which is still definitely based sensually on this one, and
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not be able to remember or understand everday reality.
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Other hallucinogenic experiences, e.g. the delerium caused by
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anti-cholinergics, might be still more intense than DMT in terms
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of being completely removed from traditional reality, but I don't
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think anyone would recommend experimenting with these dangerous
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substances.
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In terms of which is the superior hallucinogen, it depends on your
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taste. DMT is very interesting and extremely intense, but not
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necessarily pleasant. LSD has more potential for pure recreation.
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Most people would probably prefer LSD as a recreational hallucinogen,
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and it would be ill-advised for someone who was not very familiar
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with coping with the intensity of LSD to be thrust into the
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intensity of DMT. On the other hand, if you don't like DMT, you only
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have to hang on for a few minutes, whereas if you don't like LSD
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you have to hang on for several hours.
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This is, of course, apart from the dosage, all subjective.
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Jeremy
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=========================================================================
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152.94.1.10 (L`HOMBRE INVISIBLE) writes:
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>INDOLE ETHYLAMINES
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>------------------
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>Many plants contains psychedelic tryptamines :
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> Piptadenia Peregrina
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> Phalaris Grundinacea
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> Mimosa hostillis
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> Desmanthes illioiensis
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> Arundo Donax
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> etc.
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>The DMT/5-methoxy-DMT ... is often located in the roots of the plant
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Depends on the species - some contain it in the leaves or the bark.
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>My question is :
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>Is it possible to smoke the plant-material directly or do you have to
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>exctract
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>it first ?.
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I don't know as much about 5-Me-O DMT as DMT. THere is an important
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difference, which is the dose. The former is effective at about
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5mg-10mg from memory, the latter at 30-60mg. Thus, it is possible
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to obtain sufficient 5-Me-O DMT from smoking some impure unrefined
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sources (such as the poison of Bufo alvarius)..
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Considering DMT as opposed to 5-Me-O DMT (which is IMHO by far
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the more desirable material), and recalling that most people
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find the peak of a DMT trip only to last a very few minutes
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after smoking (i.e. you have to smoke it all at once, within
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a few tokes, to obtain the peak) you can easily calculate the
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necessary purity. Let us say, that one is capable of smoking
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100mg of material in a few seconds. THis means that a DMT
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containing mixture should be at least 30% pure to get sufficient
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effect, and a 5-Me-O DMT mixture should be at least 5% pure.
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In actual fact, it is not quite as bad as this, because if
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you are using a free-base pipe, you can get away with lower
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purities because the DMT is quite volatile, so initially, the
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smoking process will concentrate the DMT.
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Comparing this to plant matter, which might be e.g. 0.3% DMT,
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and you see at once, that you would need to smoke about 10 g
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in a few seconds which is unrealistic. Hence, chemical
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purification is necessary.
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The alternative is to take the plant source orally in
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combination with the hallucinogenic monoamineoxidase
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inhibitor harmaline (and related alkaloids). These
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are most readily obtained from Peganum harmala
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(or Banisteriopsis caapi) and serve to activate and
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potentiate tryptamines, increasing intensity and
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duration and giving oral activity to DMT.
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> What are the effects (Like the pure stuff (DMT)) ?
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A small amount gives a wierd feeling in the body and some
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perceptual change. A larger amount gives strong body feelings
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and heavy visual effects , somewhat similar to LSD, but
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much more based around geometry, and changes of shape
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perception. A very large dose is totally awesome, and
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people's responses differ, from catatonia, to screaming,
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to total ecstasy. Some people describe it as a religious
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experience. Many people find they completely leave our
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universe for the duration, which is generally up to 5
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minutes, with residual effects up to half an hour.
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B
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>Which plant(s) are best suited ? (Highest in DMT)
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There are various possibilities. Since chemical purification
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is generally necessary, the plant content is not vitally
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important. Most important is supply - the best species
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is one which grows locally, and in the US, the best
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source is probably Desmanthus illinoensis.
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If you wish to receive instructions on how to chemically
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purify DMT from a plant source, and more information about
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the effects of DMT, mail me at:
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but do not hassle the owner of this account by replying to
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this address.
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Jeremy
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===========================================================================
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{In article <1992Dec22.212054.16140@shearson.com>, curious@somewhere (Curious Furious) writes:
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>
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> Hi knowledgeable folks,
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> I have a few questions from a FOAF:
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>
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> 1) When smoking DMT what is the LD50 ? Can it cause a heart attack?
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>
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Certainly much higher than the amount beyond which one would have
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no concept of what a pipe, DMT, oneself, etc. is. Also much higher
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than the amount one could get into ones body by smoking before
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it was metabolised. I imagine that even if one hooked oneself
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to a machine which continously fed oxygen, nitrogen, and DMT
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vapour it would still be hard to _physically_ overdose.
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As for heart attack, I have no idea. I can imagine being
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scared to death (literally).
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> 2) Has anyone tried doing DMT while on MDMA ? Any complications ?
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No idea. However, one of the most striking things about DMT is its
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brutalness - the rush from completely baseline to another
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universe in about five seconds. Starting off baseline does
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little to alter the peak (which tends to override anything)
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but alters the severity of the onset.
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>
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> 3) Has anyone tried doing DMT while on 'rooms? Any complications ?
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Yup - similar to above, except moreso. It takes a large dose
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for the effects of the DMT to become visible over the effects of
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the trip (likewise for LSD). Also, it is harder to trip on DMT post
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psilocybin or LSD, since there is some cross tolerence.
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Some combinations with DMT are worthwhile. A couple of beers
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beforehand bluntens and deadens a little which can be very
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helpful. A good amount of heads will add to the visual
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impact, and a good amount of hash will ad to the wierdness
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and otherness. N2O & DMT is interesting, but the combination
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is generally intense enough to cause amnesia, and lack of
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any kind of regular consciousness for the period of intoxication.
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>
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> 4) In the book _Archaic Revival_, Terence McKenna mentions some studies
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> that found that DMT is produced heavily while in the deepest stages
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> of sleep. Anybody have a reference for that?
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Interesting concept. Like much of McKenna's work, I expect that
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the science to back him up is scanty, non-existant, or
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occasionally wrong. Makes for a good story, though.
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>
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> 5) Since DMT is a naturally occurring substance in the human body,
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> if a machine was created which could extract DMT from your own
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> blood, would that machine be considered illegal?
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My limited understanding of US law suggests that if humans
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contain DMT then their entire weight can be counted as DMT
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(since the carrier weight can be included)
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Such a theoretical machine as you suggest would be covered by
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paraphernalia laws?
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>
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> 6) Can any MAOI be used to render DMT active orally?
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>
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Lamont is the expert on this, and he says yes. I am not convinced,
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and I don't think there is any proper research published on
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the subject. Even in the case of the traditional harmaline/DMT
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interaction, the scientific data is minimal, and it is surmise
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only that the DMT is orally activated by the MAOI effect
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of the harmaline and not by some other effect.
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I hope someone else will fill in the missing details.
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>
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> thank you for your time.
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>
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my pleasure.
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Jeremy
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=============================================================================
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With respect to orally activating DMT with an MAOI,
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Dennis McKenna has this to say in his '84 review article in J. Psych.
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Drugs 16(4):
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"The potentiation of the behavioral and pharmacological effects of
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tryptamine derivatives by MAOIs has been investigated, although
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the specific question of the oral potentiation of DMT and other parenterally-
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active derivates has apparently not been investigated. The effects
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of DMT in human volunteers was assessed before and 3 days after treatment
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with the MAOI iproniazid (Sai-Halasz 1963). Patients receiving DMT
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at a reduced dose following the iproniazid treatment experienced
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none of the visual illusions or disturbances of time and space perception
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that typify the symptoms of the drug. They reported only a feeling of
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"strangeness." Patients receiving a dose equivalent to that prior
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to iproniazid had a two-phase response. The first stage was similar
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to the usual DMT effects, but less pronounced: illusions and hallucinations
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were present but less colorful and only manifested themselves with the
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eyes closed. The second phase was characterized by a persistent feeling
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of "strangeness" to which the patients often reacted negatively or
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indifferently. Based on these trials, Sai-Halasz (1963) speculated
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that the reduced effects may have been due to the higher 5-HT
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concentration in the brain due to MAO inhibition, thus mitigating the
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5-HT blocking effects of DMT. This speculation was also supported
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by the observation that prior administration of 1-methyl-d-lysergic acid
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butanolamide, a powerful serotonin antagonist, greatly exacerbated
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the psychotomimetic effects of DMT (Sai-Halasz 1962)."
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So, it would appear that the answer to question 6 hasn't been established.
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However, some studies (mentioned above) seem to have been done demonstrating
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an interaction between MAOIs and DMT.
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Jeremy handled most of those questions better than I could, so I
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don't have much else to add. I doubt there have been any deaths
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attributable to DMT use. Also, I don't recall endogenous DMT in humans
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and Dennis doesn't mention it in his review article so it is either
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recent (post 1984) knowledge or it is a misprint by the poster or
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publisher and should refer to a related tryptamine. Or maybe it's
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another revalation from the self-constructing machine elves.
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--M@
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===========================================================================
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This is from _The Psychedelic Guide to the Preparation of the
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Eucharist, in a few of its many guises_, as edited by Robert
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E. Brown and associates of the Neo_American Church League for
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Spiritual Development & the Ultimate Authority of the Clear
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Light (1968), 2nd edition (1971)
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DMT Synthesis
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STEP I
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Using an area of good ventilation or a fume hood, place a
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1000 ml two hole roundbottom flask in an ice bath using the
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setup in Figure II (you want a wobble stirrer in the top hole
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of the flask, and a separatory dropping funnel into the side
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entry). Add 400 ml cold anhydrous ether to the flask, in which
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60 g indole is then dissolved, using the stirrer. To 100 ml
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anhydrous ether in a separatory funnel add 50 g oxalyl
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chloride. Slowly drip this solution into the vigorously
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stirred indole solution over a period of 10 to 15 minutes.
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Continue stirring 10 minutes longer. Allow the precipitate to
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settle a few minutes and decant the liquid. Add anhydrous
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ether and mix well. When satisfied as to the purity of the
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precipitate, leave the golden precipitate in the flask for the
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next step, which must follow immediately. Yield is
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approximately 100 g.
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STEP II
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Dimethylamine reacts readily with indole oxalyl chloride.
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Use about 400 ml ice cold anhydrous ether in the same 2 neck
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1000 ml RB flask used in Step I, with the precipitate in it
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from Step I. Cool the ice bath further by using salt and ice.
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Estimate the weight of the precipitate and use 100 g indole
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oxalyl chloride. For this weight of IOC use two entire 50 g
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containers of diethylamine since it will not keep if the
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container seal is broken. Cool the amine in container much
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below 0 C and dissolve 1 part amine in 3 parts anhydrous cold
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ether. Amine may be stored in this solution. For use, warm
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stock solution to room temperature and use the appropriate
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aliquot. Set up the entire apparatus the same as when adding
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the oxalyl chloride. Add the amine solution slowly to the IOC
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with vigorous stirring. Stir for 1/2 hour after the addition
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is complete. Vacuum filter the precipitate, using ether as a
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wash. It is better to slurry the ether water with the
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precipitate before filtering [method used]. Recrystallise from
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hot ethanol or from a 50-50 methanol-benzene mixture.
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STEP III
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Prepare apparatus as in Figure II (1-hole 1000 ml RB
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flask set in heating mantle on magnetic stirrer with stir bar
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in flask, and condenser inserted into top of flask). Prepare
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the indole glyoxyl amide by melting and casting into sticks if
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ether is to be used as a solvent. Aluminium foil makes a good
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mould for casting pieces that will fit through the condenser.
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Also a Soxhlet extractor may be used to add the crystals by
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slow solution into the ether. Tetrahydrofluran, if available,
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dissolves IGA and the compound is added slowly in the solution
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form [method used].
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To a stirred mixture of 15 g LiAlH4 in 100 ml anhydrous
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ether (or THF [used]) slowly add the sticks (or solution
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[used]) of IGA until 20 g have been added. Keep the rate of
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reaction at a reasonable rate or boil-over may occur [do
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say!]. Stir and reflux for 90 minutes after the addition is
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complete. Cool in an ice bath and begin to cautiously [do
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say!] hydrolyse with chips of ice or a cold solution of
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methanol, added through the condenser. When there is no
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further reaction, add a few ml extra water and allow to settle
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finally and decant the clear liquid into an evaporating
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vessel. Filter the residue and wash several times with
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ether-methanol or THF-methanol [used]. Evaporate the combined
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extracts and if necessary, seed the heavy syrup with crystals
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of DMT. With no seed crystals the product may take days or
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even weeks to crystallise [weeks]. This crude product is
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adequate for smoking [do say!]. In order to purify DMT, begin
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after the LiAlH4 has been hydrolysed with methanol. Add 500 ml
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satd. Na2SO4 solution, mix and filter. Wash with ether or THF
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and neutralise the filtrate with 0.1 N HCl. Extract with ether
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in a separatory funnel and neutralise the lower layer with 0.1
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N NaOh, extracting this solution in turn with chloroform. The
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chloroform layer is dried over anhydrous Na2SO4, concentrated,
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and from it DMT crystallises on addition of petroleum ether.
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The mother liquor can be chromatographed on an alumina column
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using benzene-methanol in a 99.8 to 0.2 ratio. [This last
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purification is quite difficult.]
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--
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John Collier Email: jcollier@ariel.ucs.unimelb.edu.au
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HPS -- U. of Melbourne Fax: 61+3 344 7959
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Parkville, Victoria, AUSTRALIA 3052
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=============================================================================
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Newsgroups: alt.drugs
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From: Jeremy
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Subject: Re: DMT Ingestion Methods
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Date: Thu, 1 Jul 1993 14:53:35 GMT
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DMT is a powerful hallucinogen. No one should take it for granted
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or use it lightly. It is also illegal, although natural sources
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are uncontrolled.
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In article <1993Jul1.020634.2524@mixcom.mixcom.com> Nathan.Bowen <Nathan.Bowen@mixcom.mixcom.com> writes:
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> Lately, there has been an increasing interest among alt.drugs
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>posters concerning DMT in its many forms. I'm finding the many accounts
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>of experiences quite intriguing, but I am still pretty thoroughly in the
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>dark concerning methods of usage. I believe I understand to a
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>reasonable extent the various methods themselves, but I cannot find
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>sufficient information on the benefits or drawbacks of them. I seek
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>both scientific evidence and subjective reports of the desirability of
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>given methods from people who are in a position to know.
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>
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> In my understanding, eating/drinking is probably the least desirable
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>method, in that it requires a monoamine oxidase inhibitor to be active
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>orally.
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Each method of ingestion has its own advantages and disadvantages.
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Oral DMT/harmaline is potentially the best method of ingestion
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in terms of having a truely profound experience of useful duration.
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Coming on to the experience a little more slowly gives the user
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some time to adjust and to cope with and explore the altered state.
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Oral DMT is probably the only viable route for most alt.drugs
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readers, who can obtain the plants but who don't have the necessary
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experience and equipment to sufficiently purify DMT for smoking,
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and who do not have access to synthetic DMT.
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Unfortunately, the liquors produced by boiling up plant DMT
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sources may well make the user puke.
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Although an account of a very successful ayahuasca experience
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>was recently posted that confirmed the possibility of desirable effects
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>resulting from oral consumption, the prolonging effect of the
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>preparation involved seems to undermine the highly-acclaimed temporariness
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>of the DMT experience (hence the Businessman's Trip).
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>
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Well, the temporariness makes the intensity bareable when the
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material is smoked. The oral experience is gentler, but just
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as profound, if not moreso. Smoked DMT is so brutal, and the
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effect can be so profound, that after much experience, all I
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could say was that I couldn't say anything adequate about it,
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and so I gave up on it.
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> The most common form of ingestion, at least among the accounts on
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>the 'net, is smoking. There are inherent disadvantages to inhaling the
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>gases given off by burning matter, but I don't see any way around it,
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>and it seems that smoking is also the most accepted method for a
|
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>pleasurable experience.
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Don't make the mistake of calling DMT pleasurable - that may
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|
or may not be one of its side-effects :). In fact,
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|
apart from the physical, smoked DMT is more likely to be
|
|
dysphoric than oral DMT. A single user may have one DMT
|
|
trip which is totally orgasmic, and then another which is
|
|
totally horrific, and then another that is neither.
|
|
Smoking the chemical is particularly unpleasant to the
|
|
mouth, throat, and lungs, and some people find it an
|
|
impossible task.
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|
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I don't see how, logically, a water bong or
|
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>some such device could be implemented here, but I'm definitely willing
|
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>(and eager) to be proven wrong.
|
|
>
|
|
Hot DMT vapours are somewhat soluble in water; if you are smoking
|
|
the chemical, then mostly what you are getting is its vapour, and
|
|
there is little you can do to improve the quality.
|
|
|
|
> The other methods that have been mentioned are snuffs (a la the
|
|
>native South American rituals)
|
|
|
|
The South American snuffs contained various tryptamines. It is
|
|
well nigh impossible to get a sufficient dose of DMT from a
|
|
snuffed plant source - the concentrations just aren't high
|
|
enough. Likewise smoking a plant. The major active in the
|
|
snuffs was probably 5-MeO-DMT.
|
|
|
|
and injection (for which I can find no
|
|
>references).
|
|
|
|
Lots of experiments in the 60's. If you have something pure
|
|
enough to inject, you might as well smoke it and save yourself
|
|
the hassle. Likewise, there is probably little advantage to
|
|
snorting the pure chemical over smoking it.
|
|
|
|
Jeremy
|
|
|
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=============================================================================
|
|
|
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Newsgroups: alt.drugs
|
|
From: pierre@media.mit.edu (Pierre St. Hilaire)
|
|
Subject: Re: DMT Ingestion Methods
|
|
Message-ID: <1993Jul1.145039.5758@news.media.mit.edu>
|
|
Date: Thu, 1 Jul 1993 14:50:39 GMT
|
|
|
|
> The other methods that have been mentioned are snuffs (a la the
|
|
>native South American rituals) and injection (for which I can find no
|
|
>references). The snuffs have been reputed as bringing on rapid and
|
|
>powerful effects, and that seems to correspond with my knowledge of
|
|
>snuffed/injected drugs. I do not, unfortunately, have a sufficient
|
|
>amount of information on the safety of these methods. I do understand
|
|
>the inherent dangers of sending the material directly to your
|
|
>bloodstream, in that any impurities will follow just as easily. Other
|
|
>than that, I am fairly in the dark. This is where the bulk of my
|
|
>request lies. Are these methods as efficient and desirable as they seem
|
|
>at the outset? And, even if they aren't, how do they rank with oral use
|
|
>or smoking? Opinions are as welcome as facts, and any reply will be
|
|
>greatly appreciated. If I get a large enough response, I'll try to
|
|
>compile a FAQ or short informational file of some sort.
|
|
>
|
|
|
|
My experiences and those of others point to the fact that the
|
|
subjective effects of tryptamines vary markedly with the route of
|
|
absorbtion. While smoking often results in overwhelming experiences it
|
|
is possible to have more psylocibin like effects by snorting or eating
|
|
small amounts in conjunction with P harmala seeds. It seems also that
|
|
5-MeO-DMT and DMT, whose effects differ considerably when smoked, seem
|
|
to "converge" in subjective effects when taken orally. I wonder if
|
|
other knowledgeable people on the net could substanciate that last
|
|
claim.
|
|
|
|
Of all the psychedelics, short acting tryptamines seem to have
|
|
the most non linear dose-responses curve. Taking twice a barely active
|
|
dose will often result in an intense experience! That is the reason
|
|
why you should be very careful when taking them orally.
|
|
|
|
I recently found a very interesting and potentially safer way
|
|
to use 5-MeO-DMT. The key is to dissolve it in distilled water and put
|
|
the solution in one of those nose spray bottles in such a way that
|
|
each inhalation will dispense about 3-4 mg (Don't screw up there!).
|
|
When taken as a nose spray the effects come on more slowly than smoked
|
|
(about 1 min. instead of a few sec.) and the effect is more spread out
|
|
in time. The nice thing is that it is possible to very accurately
|
|
control the dose, which makes the trip a lot more manageable. Taken in
|
|
that manner, the effect can be fairly similar to psilocybin, with the
|
|
advantage that it is possible to come down within half an hour. I
|
|
guess this method could be used with DMT, but you would probably have
|
|
to convert the base into a salt (for higher solubility) since you need a
|
|
10x higher concentration of DMT in the solution.
|
|
|
|
Pierre St Hilaire
|
|
MIT Media Lab
|
|
|
|
=============================================================================
|
|
|
|
From: hatter@cs.utexas.edu (John Eichenseer)
|
|
Newsgroups: alt.drugs
|
|
Subject: Re: DMT extraction
|
|
Date: 11 May 1994 13:19:35 -0500
|
|
Message-ID: <2qr7jn$29f@saltillo.cs.utexas.edu>
|
|
|
|
>I am trying to extract DMT from Desmanthus illinoensis.
|
|
|
|
Ah, good luck, and do post your results...
|
|
|
|
> So, what do you think? Will this method work? Is there any
|
|
>better way that is easier (this is pretty easy) or more efficient?
|
|
|
|
In his book Pharmacotheon, Jonathan Ott mentions experiments in which
|
|
he extracted the alkaloids via boiling water. In fact, I think he may
|
|
have just strained hot water through the finely ground material, like
|
|
making coffee. He did this in order to mix it with an MAOI (harmala
|
|
seeds) for oral ingestion. I believe he goes into much more detail in
|
|
his latest book, Ayahuasca Analogs.
|
|
|
|
Can anybody comment on the viability of this technique? It does seem
|
|
even easier than the acid-base extracion, although of course it would
|
|
not yield the smokable freebase.
|
|
|
|
Just curious,
|
|
|
|
jhno
|
|
|
|
=============================================================================
|
|
|
|
rpascazi@engws3.ic.sunysb.edu (Robert R Pascazio) writes:
|
|
|
|
> Has anybody heard stories about Arundo donax (aka "Giant Reed") ? It
|
|
> is rummored to contain DMT and other exciting Alkaloids.
|
|
|
|
Yes. It contains some DMT, but not very much. Someone told me the other
|
|
day that a friend of theirs that is investigating this (solicited samples
|
|
from interested parties, and used thin layer chromatography to assay the
|
|
root stocks, from what I was told) says there's "little or no DMT" in
|
|
Arundo donax rhizomes.
|
|
|
|
The paper that first found DMT and a few other indole alkaloids in Arundo
|
|
donax (Ghosal) working in India (River Reed is used in Ayurvedic
|
|
medicine) also found only trace amounts. You'd have to extract several
|
|
kilograms to get a psychoactive dose of DMT. There are also several
|
|
cardioactive glycosides and other substances that would produce annoying
|
|
side effects if a crude extract were consumed - the effect of Arundo
|
|
donax extract on heart muscle (another paper by Ghosal et. al.) gave me
|
|
the impression that crude Arundo extracts are potentially dangerous.
|
|
You'd have to resort to solvent extraction followed by column
|
|
chromatography to extract pure DMT from the roots - a process probably
|
|
requiring several liters of solvent just to produce one dose of DMT.
|
|
|
|
I'll shell to DOS here and see if I can find my notes about Arundo
|
|
donax...
|
|
|
|
ok... here's a good starting point if you want to look into this:
|
|
--------------------------------------------------------------------
|
|
DMT in Arundo Donax / Giant River Reed
|
|
-------------------------------------------------------------------
|
|
SMITH TA
|
|
"Tryptamines and Related Compounds in Plants"
|
|
Phytochemistry, 1977, Vol.16 pp 171-175
|
|
|
|
ABSTRACT: The occurrence of the tryptamines and related compounds in
|
|
fungi
|
|
and higher plants is listed on a taxonomic basis. Several of
|
|
these
|
|
amines have considerable physiological activity in higher
|
|
animals.
|
|
|
|
Gramineae:
|
|
Arundo donax L. (Leaf,Flower,Rhizome) [27-30]
|
|
Methoxy-N-methyl-Tryptamine
|
|
DMT
|
|
DMT-Methohydroxide
|
|
Bufotenine
|
|
DMT-N-oxide
|
|
Bufotenidine
|
|
Dehydrobufotenine
|
|
Gramine
|
|
Gramine-N-oxide
|
|
Gramine methohydroxide
|
|
|
|
[27] OREKHOV AP, NORKINA SS (1937) Zhur.Obsch.Chem. 7,673
|
|
[28] GHOSAL S, BANERJEE PK, BANERJEE SK (1970) Phytochemistry 9,429
|
|
[29] GHOSAL S, CHAUDHURI RK, DUTTA SK (1971) Phytochemistry 10,2857
|
|
[30] GHOSAL S, CHAUDHURI RK, DUTTA SK, BATTACHARYA SK (1972) Planta Med.
|
|
21,22
|
|
--------------------------------------
|
|
|
|
Tryptamines in the Graminacea:
|
|
|
|
Arundo donax - Giant River Reed
|
|
Phalaris arundinacea
|
|
|
|
|
|
_A Handbook of Alkaloids and Alkaloid Containing Plants_
|
|
Wiley Interscience, Raffauf QK898.A4 R34 (1970)
|
|
|
|
|
|
N,N-DMT GRAM-028A refs:1946, 573
|
|
N,N-DMT-5-MeO GRAM-030A
|
|
Bufotenine GRAM-030A refs:1945
|
|
Gramine GRAM-016A
|
|
|
|
|
|
573 Aus J. Chem 17:1301 (1964) [Phalaris]
|
|
416 Aus J. Chem 19:893 (1966) [Phalaris]
|
|
|
|
1946 Dutta,SK;Ghosal,S _Chem.Ind._ (1967) p2046
|
|
1945 Moore,RM; Williams,JD; Chia,J _Chem.Abst._ 68:75704v (1968)
|
|
|
|
574 Ghosal,S; Mukhergee,BB _Chem.Ind._ (1965), 793
|
|
575 Morinato,H; Matsumoto,N _Am.Chem._ 692 p194 (1966)
|
|
|
|
464 Legler,G; Tschesche,R _Naturwiss_ 94 (1963)
|
|
|
|
===============================================================
|
|
|
|
REFERENCES:
|
|
|
|
_Tryptamine and related compounds in plants._ SMITH, TA.
|
|
"Phytochemistry." vol.16 pp.171-175. (1977) QK861.P45
|
|
|
|
_The Occurrence of Indolealkylamine Alkaloids in Phalaris tuberosa L. and
|
|
P. arundinacea L._ , Culvenor,Dal Bon & Smith
|
|
"Australian Journal of Chemistry" 1964, Vol.17 pp.1301-4
|
|
|
|
_Heterocyclic Compounds, Indoles, Part 2_ Houlihan, Wiley Interscience,
|
|
pg264
|
|
|
|
_Indole alkaloids in plant hallucinogens_ Schultes, Richard Evans
|
|
"Journal of Psychedelic Drugs" Jan-Mar 1976 p17
|
|
|
|
_Plants of the Gods_ Schultes & Hofmann
|
|
|
|
_Narcotic Plants_ William Emboden
|
|
|
|
_Tryptamine and Related Compounds in Plants_
|
|
Terence A. Smith. "Phytochemistry" Vol. 16 pp. 171-175
|
|
|
|
_Alkaloid Bearing Plants and Their Alkaloids_
|
|
US Dept. Agriculture Technical Bulletin No. 1234 (1961) Willaman &
|
|
Schubert
|
|
|
|
Erspamer _???? Drug Res._ 1961,3,151
|
|
|
|
=============================================================================
|
|
|
|
From: rocky.frisco@bgbbs.com (Rocky Frisco)
|
|
Newsgroups: alt.drugs
|
|
Subject: Ayahuasca....more info ne
|
|
Message-ID: <67.15287.706.0N3ED642@bgbbs.com>
|
|
Date: 29 Jan 94 02:37:00 GMT
|
|
|
|
AA> Thank you everyone who e-mailed me information on Yaje. If anyone
|
|
AA> else has more info, I still need it. Please post or e-mail me. I
|
|
AA> would especially like to hear from people who have experimented with
|
|
AA> Yaje. Did you smoke it or did you drink it? Thanks, Ayleen
|
|
AA> a-crotty@uiuc.edu
|
|
|
|
I think it's usually spelled "Yage" pronounced Yah-hey.
|
|
|
|
See the books "Wizard of the Amazon" and "Rio Tigre" by the late Doctor
|
|
Bruce Lamb of Santa Fe NM. (Bruce died during the Christmas Holiday
|
|
season of 1992). These are the best resources on the subject and are
|
|
written by a fine scientist who tried Ayahuasca and found it to be of
|
|
great value.
|
|
|
|
-Rock rocky.frisco@bgbbs.com
|
|
* RM 1.2 * Eval Day 7 * RoboMail -- The nag nag nag
|
|
|
|
|