61 lines
3.9 KiB
Plaintext
61 lines
3.9 KiB
Plaintext
From Legal Highs by The Twentieth Century Alchemist, published sometime in the
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early 1970's:
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DANGEROUS COMBINATIONS
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Unless one is very experienced in pharmacology, it is unwise to
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experiment with combinations of drugs. Even when using a single drug, thought
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should be given to all substances, both food and drug, which have been taken
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recently. Most primitive people fast or at least abstain from certain
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substances for several days prior to taking a sacrament. Substances most
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universally avoides are alcohol, coffee, meat, fat and salt. Some drugs
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potentiate others. For example, atropine will increase the potency of
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mescaline, harmine, cannabis and the opiates. Many of the substances
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discussed in this book are MAO inhibitors. MAO (monoamine oxidase) is and
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enzyme produced in the body which breaks down certain amines and renders them
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harmless and ineffective. An MAO inhibitor interferes with the protective
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enzyme and leaves the body vulnerable to these amines. A common substance
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such as tyramine, which is usually metabolized with little or no
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pharmacological effect, may become dangerous in the presence of an MAO
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innhibitor and cause headache, stiff neck, cardiovascular difficulties, and
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even death. MAO inhibitors may intensify and prolong the effects of other
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drugs (CNS depressants, narcotic analgesics, anticholinergics, dibenzazepine
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antidepressants, etc.) by interfering with their metabolism. In the presence
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of an MAO inhibitor many substances which are ordinarily non-active because of
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their swift metabolism may become potent psychoactive drugs. This phenomenon
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may creat a new series of mind alterants. However, because of the complex and
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precarious variables involved, it is risky and foolish for anyone to
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experiment with these possibilities on the non-professional level.
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The most commonly used MAO inhibitors include hydrazines such as
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iproniazid, Marsilid, Marplan, Niamid, Nardil, Catron; also non-hydrazines
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such as propargylamines, cyclopropylamines, aminopyrazine derivatives,
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indolealkylamines, and carbolines. MAO inhibiting materials discussed in this
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book include yohimbine, various tryptamines, especially 5-MeO-DMT and the
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alpha-methyltryptamines, and the various harmala alkaloids. The latter are
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especially potent inhibitors, but, like yohimbine and the tryptamines, are
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short-lasting in action (30 minutes to several hours). Some of the commercial
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MAO inhibitors listed above are effective for several days to several weeks.
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Among the material which may be dangerous in combination with MAO
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inhibitors are sedatives, tranquilizers, antihistamines, narcotics and
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alcohol--any of which can cause hypotensive crises (severe blood pressure
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drop); and amphetamines (even diet pills), mascaline, asarone, nutmeg (active
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doses), macromerine, ephedrine, oils of dill, parsley or wild fennel, beer,
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wine, cocoa, aged cheeses and other tyrosine-containing foods (tyrosine is
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converted to tyramine by bacteria in the bowel)--any of which can cause
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hypertensive crises (severe blood pressure rise).
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X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X
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Another file downloaded from: The NIRVANAnet(tm) Seven
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& the Temple of the Screaming Electron Taipan Enigma 510/935-5845
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Burn This Flag Zardoz 408/363-9766
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realitycheck Poindexter Fortran 510/527-1662
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Lies Unlimited Mick Freen 801/278-2699
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The New Dork Sublime Biffnix 415/864-DORK
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The Shrine Rif Raf 206/794-6674
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Planet Mirth Simon Jester 510/786-6560
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"Raw Data for Raw Nerves"
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X-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-X
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